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  1. Postoperative delirium (POD) is a common phenomenon after spinal surgery. Intraoperative fluid management may affect POD. The aim of this study was to compare the effects of restrictive fluid therapy (RF) with...

    Authors: Duo Duo Wang, Yun Li, Xian Wen Hu, Mu Chun Zhang, Xing Mei Xu and Jia Tang
    Citation: Perioperative Medicine 2021 10:48
  2. No surgical intervention is without risk. Readmissions and reoperations after elective orthopedic surgery are common and are also stressful for the patient. It has been shown that a comprehensive ortho-medical...

    Authors: Felix Rohrer, David Haddenbruch, Hubert Noetzli, Brigitta Gahl, Andreas Limacher, Tanja Hermann and Jan Bruegger
    Citation: Perioperative Medicine 2021 10:47
  3. Anxiety in children triggered by a scheduled surgical intervention is a major issue due to its frequency and consequences. Preoperative anxiety is associated with increased patient fear and agitation on anesth...

    Authors: Alberto Vieco-García, Amanda López-Picado, Manuel Fuentes, Laura Francisco-González, Belén Joyanes, Carmen Soto, Ana Garcia de la Aldea, Carlos Gonzalez-Perrino and Esther Aleo
    Citation: Perioperative Medicine 2021 10:58
  4. Perioperative acute kidney injury (AKI) is associated with multiple postoperative complications leading to prolonged hospital stay and higher costs. AKI requiring continuous renal replacement therapy (CRRT) af...

    Authors: Panu Uusalo, Tapio Hellman and Mikko J. Järvisalo
    Citation: Perioperative Medicine 2021 10:57
  5. This meta-analysis aimed to evaluate the efficacy and safety of antimuscarinics for the prevention or treatment of catheter related bladder discomfort (CRBD).

    Authors: Zhongbao Zhou, Yuanshan Cui, Xiaoyi Zhang, Youyi Lu, Zhipeng Chen and Yong Zhang
    Citation: Perioperative Medicine 2021 10:46
  6. Postoperative ileus (POI) is associated with increased patient discomfort, length of stay (LOS), and healthcare cost. There is a paucity of literature examining POI in patients who have an ileostomy formed at ...

    Authors: Anya L. Greenberg, Yvonne M. Kelly, Rachel E. McKay, Madhulika G. Varma and Ankit Sarin
    Citation: Perioperative Medicine 2021 10:55
  7. Remote ischemic preconditioning (RIPC) has been suggested to confer neuroprotective effect. However, influences of RIPC on postoperative delirium (POD) and cognitive dysfunction (POCD) in adults after cardiac ...

    Authors: Yuchen Jing, Bai Gao and Xi Li
    Citation: Perioperative Medicine 2021 10:50
  8. TOFscan is a three-dimensional acceleromyography neuromuscular monitoring device that does not require initial calibration before muscle relaxant injection. This study aimed to compare TOFscan with TOF-Watch S...

    Authors: Hyung-Been Yhim, Young-Eun Jang, Ji-Hyun Lee, Eun-Hee Kim, Jin-Tae Kim and Hee-Soo Kim
    Citation: Perioperative Medicine 2021 10:45
  9. To assess whether different intensities of intra-abdominal pressure and deep neuromuscular blockade influence the risk of intra-operative surgical complications during laparoscopic donor nephrectomy.

    Authors: Gabby T. J. A. Reijnders-Boerboom, Esmee V. van Helden, Robert C. Minnee, Kim I. Albers, Moira H. D. Bruintjes, Albert Dahan, Chris H. Martini, Frank C. H. d’Ancona, Gert-Jan Scheffer, Christiaan Keijzer and Michiel C. Warlé
    Citation: Perioperative Medicine 2021 10:56
  10. Although dexmedetomidine (Dex) is known to reduce bispectral index (BIS) values and propofol dosage, there is little information regarding raw electroencephalography (EEG) changes related to Dex deepening of p...

    Authors: Lei Zhang, Kun Fang, Shengwei Tao, Liyun Deng, Hua Li, Yuanyuan Cao, Lei Wang, Fengqiong Yu and Erwei Gu
    Citation: Perioperative Medicine 2021 10:44
  11. Psychological factors like anxiety and depression are recognised to play a causal role in the development of cardiovascular disease and they may also influence outcome after vascular surgery procedures. The ai...

    Authors: Manuela Aspalter, Florian K. Enzmann, Thomas J. Hölzenbein, Wolfgang Hitzl, Florian Primavesi, Lucia Algayerova, Patrick Nierlich, Christoph Kartnig, Reinald Seitelberger and Klaus Linni
    Citation: Perioperative Medicine 2021 10:53
  12. Delirium is an important postoperative complication. Recent research suggested that 5-hydroxytryptamine 3 (5-HT3) receptor antagonists may have clinical effect in the treatment and prevention of delirium. We inve...

    Authors: Hyun-Jung Shin, Jiwon Yoon and Hyo-Seok Na
    Citation: Perioperative Medicine 2021 10:51
  13. The incidence of postoperative pulmonary complications (PPCs) is increasing in line with the rise in the number of surgical procedures performed on geriatric patients. In this study, we determined the incidenc...

    Authors: Jitsupa Nithiuthai, Arunotai Siriussawakul, Rangsinee Junkai, Nutthakorn Horugsa, Sunit Jarungjitaree and Namtip Triyasunant
    Citation: Perioperative Medicine 2021 10:43
  14. Procedural sedation reduces patients’ discomfort and anxiety, facilitating performance of the examination and intervention. However, it may also cause adverse events, including airway obstruction and hypoxia. ...

    Authors: Hsin-Yi Liu, Ka-Wai Tam, El-Wui Loh, Wan-Chi Liu, Hsien-Cheng Kuo, Chun-Cheng Li, Yih-Giun Cherng, Jui-Tai Chen and Ying-Hsuan Tai
    Citation: Perioperative Medicine 2021 10:41
  15. Hyperspectral imaging (HSI) could provide extended haemodynamic monitoring of perioperative tissue oxygenation and tissue water content to visualize effects of haemodynamic therapy and surgical trauma. The obj...

    Authors: Maximilian Dietrich, Sebastian Marx, Maik von der Forst, Thomas Bruckner, Felix C. F. Schmitt, Mascha O. Fiedler, Felix Nickel, Alexander Studier-Fischer, Beat P. Müller-Stich, Thilo Hackert, Thorsten Brenner, Markus A. Weigand, Florian Uhle and Karsten Schmidt
    Citation: Perioperative Medicine 2021 10:42
  16. This study sought to assess feasibility of a randomized trial of blood pressure intervention (home blood pressure monitoring vs. counseling) in the preoperative clinic and the baseline rates of primary care fo...

    Authors: Sofia I. Diaz, Luying Yan, Feng Dai, Bin Zhou, Matthew M. Burg and Robert B. Schonberger
    Citation: Perioperative Medicine 2021 10:39
  17. Enhanced recovery after surgery (ERAS) pathways have emerged as a promising strategy to reduce postoperative opioid use and decrease the risk of developing new persistent opioid use in surgical patients. Howev...

    Authors: E. M. Langnas, Z. A. Matthay, A. Lin, M. W. Harbell, R. Croci, R. Rodriguez-Monguio and C. L. Chen
    Citation: Perioperative Medicine 2021 10:38
  18. Homocysteine, folate, and vitamin B12 involved in 1-carbon metabolism are associated with cognitive disorders. We sought to investigate the relationships between these factors and delayed neurocognitive recovery ...

    Authors: Zhen-Feng Zhang, Qing-Chun Sun, Yi-Fan Xu, Ke Ding, Meng-Meng Dong, Liu Han, Abdul-Mannan, Yuan Han and Jun-Li Cao
    Citation: Perioperative Medicine 2021 10:37
  19. Family-centered care has been considered as a philosophy of care. Family presence in intensive care units (ICUs), especially in the acute phase of the disease is controversial. This study has been carried out ...

    Authors: Jamileh Mokhtari Nouri, Leila Safaeipour, Zohreh Vafadar and Seyed Tayeb Moradian
    Citation: Perioperative Medicine 2021 10:40
  20. Preoperative education and breathing exercise training by a physiotherapist minimises pulmonary complications after abdominal surgery. Effects on specific clinical outcomes such as antibiotic prescriptions, ch...

    Authors: I. Boden, J. Reeve, I. K. Robertson, L. Browning, E. H. Skinner, L. Anderson, C. Hill, D. Story and L. Denehy
    Citation: Perioperative Medicine 2021 10:36
  21. Treatment of high-risk pulmonary embolism (PE) in perioperative patients remains challenging. Systemic thrombolysis is associated with a high risk of major bleedings and intracranial haemorrhage. High mortalit...

    Authors: Götz Schmidt, Fabian Edinger, Christian Koch, Matthias Wolff, Christoph Biehl, Rüdiger Hörbelt and Michael Sander
    Citation: Perioperative Medicine 2021 10:35
  22. Surgical resection is currently the cornerstone of hepato-pancreato-biliary (HPB) cancer treatment. A low preoperative aerobic fitness level has been identified as a modifiable risk factor associated with comp...

    Authors: Caspar F. Mylius, Wim P. Krijnen, Tim Takken, Daan J. Lips, Hasan Eker, Cees P. van der Schans and Joost M. Klaase
    Citation: Perioperative Medicine 2021 10:33
  23. The influence of sugammadex for reversal of neuromuscular block (NMB) on postoperative pulmonary complications (PPCs), compared with neostigmine, remains to be determined. We performed a meta-analysis of rando...

    Authors: Jia-Feng Wang, Zhen-Zhen Zhao, Zheng-Yu Jiang, Hui-Xing Liu and Xiao-Ming Deng
    Citation: Perioperative Medicine 2021 10:32
  24. Enhanced recovery programme (ERP) after surgery needs development in Assistance Publique Hôpitaux de Paris (APHP).

    Authors: Hakim Harkouk, Perrine Capmas, Nawal Derridj, Anissa Belbachir, Lionelle Nkam, Philippe Aegerter, Eva Battaglia, Laure Tharel and Dominique Fletcher
    Citation: Perioperative Medicine 2021 10:29
  25. Minimally invasive surgery combined with enhanced recovery programmes has improved outcomes after lung cancer surgery and where early mobilisation may be an important factor. However, little is known about pul...

    Authors: Lin Huang, Henrik Kehlet and René Horsleben Petersen
    Citation: Perioperative Medicine 2021 10:26
  26. Functional endoscopic sinus surgery (FESS) is required to minimize bleeding to maintain a clear operative field during surgery, so it is important to preoperative anti-anxiety and stable hemodynamics. Initial ...

    Authors: Yang Yang, Yuling Li, Haibin Zhang, Yong Xu and Binquan Wang
    Citation: Perioperative Medicine 2021 10:28
  27. Fasting prior to anesthesia is considered aspiration prophylaxis. However, prolonged food and drink restrictions may increase the risk of other complications. The aim of this study was to assess whether a carb...

    Authors: Jakub Kukliński, Karol P. Steckiewicz, Bartosz Sekuła, Aleksander Aszkiełowicz and Radosław Owczuk
    Citation: Perioperative Medicine 2021 10:27
  28. Hyponatraemia, defined as a serum sodium [Na] concentration below 135 mmol/L, is common following surgery. As inpatient peri-operative stays shorten, there is a need to recognise pre-operative risk factors for...

    Authors: Emma Cunningham, Nicola Gallagher, Paul Hamilton, Leeann Bryce and David Beverland
    Citation: Perioperative Medicine 2021 10:25
  29. Emergency laparotomy carries a significant risk profile around the time of surgery. This research aimed to establish the feasibility of recruitment to a study using validated scoring tools to assess complicati...

    Authors: D. I. Saunders, R. C. F. Sinclair, B. Griffiths, E. Pugh, D. Harji, B. Salas, H. Reed and C. Scott
    Citation: Perioperative Medicine 2021 10:22
  30. Acute ischemic thromboembolic stroke is one of the most feared complications of atrial fibrillation (AF), and the risk increases with higher CHA2DS2-VASc scores. Postoperative atrial fibrillation (POAF) is com...

    Authors: Jennifer Mardini, Melanio Bruceta, William Parrella-O’Donnell and Kunal Karamchandani
    Citation: Perioperative Medicine 2021 10:17
  31. Postoperative heart failure (PHF) is the main cause for mortality after cardiac surgery but unbiased evaluation of PHF is difficult. We investigated the utility of postoperative NT-proBNP as an objective marke...

    Authors: Huiqi Jiang, Jonas Holm, Örjan Friberg, Farkas Vanky, Mårten Vidlund, Bashir Tajik, Yanqi Yang and Rolf Svedjeholm
    Citation: Perioperative Medicine 2021 10:21
  32. Evidence suggests that unhealthy lifestyle behaviours are modifiable risk factors for postoperative complications. Digital behaviour change interventions (DBCIs), for instance text messaging programs and smart...

    Authors: Katarina Ã…sberg and Marcus Bendtsen
    Citation: Perioperative Medicine 2021 10:18
  33. The EMPOWER trial aimed to assess the effects of a 9-week exercise prehabilitation programme on physical fitness compared with a usual care control group. Secondary aims were to investigate the effect of (1) t...

    Authors: Lisa Loughney, Malcolm A. West, Helen Moyses, Andrew Bates, Graham J. Kemp, Lesley Hawkins, Judit Varkonyi-Sepp, Shaunna Burke, Christopher P. Barben, Peter M. Calverley, Trevor Cox, Daniel H. Palmer, Michael G. Mythen, Michael P. W. Grocott and Sandy Jack
    Citation: Perioperative Medicine 2021 10:23
  34. Group education is increasing in popularity as a means of preparing patients for surgery. In recent years, these ‘surgery schools’ have evolved from primarily informing patients of what to expect before and af...

    Authors: I. Fecher-Jones, C. Grimmett, F. J. Carter, D. H. Conway, D. Z. H. Levett and J. A. Moore
    Citation: Perioperative Medicine 2021 10:20
  35. The superiority of either the traditional or Stewart based approach to acid-base balance has focused primarily on analyzing metabolic acidemia, with little attention given to patients with neutral pH. In this ...

    Authors: Joost W. Janssen, Joris M. K. van Fessem, Tijmen Ris, Robert Jan Stolker and Markus Klimek
    Citation: Perioperative Medicine 2021 10:15
  36. Carbohydrate-containing drinks (CCD) are administered preoperatively in most enhanced recovery after surgery (ERAS) programs. It is not known which types of CCDs are used, e.g., simple vs. complex carbohydrate...

    Authors: Sunitha M. Singh, Asha Liverpool, Jamie L. Romeiser, Joshua D. Miller, Julie Thacker, Tong J. Gan and Elliott Bennett-Guerrero
    Citation: Perioperative Medicine 2021 10:19
  37. Postoperative acute kidney injury (PO-AKI) is a leading cause of short- and long-term morbidity and mortality, as well as progression to chronic kidney disease (CKD). The aim of this study was to explore the p...

    Authors: Gianluca Villa, Silvia De Rosa, Caterina Scirè Calabrisotto, Alessandro Nerini, Thomas Saitta, Dario Degl’Innocenti, Laura Paparella, Vittorio Bocciero, Marco Allinovi, Angelo R. De Gaudio, Marlies Ostermann and Stefano Romagnoli
    Citation: Perioperative Medicine 2021 10:13
  38. The safety of perioperative intravenous hydroxyethyl starch (HES) products, specifically HES 130/0.4, continues to be the source of much debate. The aim of this meta-analysis was to update the existing evidenc...

    Authors: Yi Xu, Siying Wang, Leilei He, Hong Yu and Hai Yu
    Citation: Perioperative Medicine 2021 10:16
  39. Inadequate neuromuscular recovery might impair pulmonary function among adult patients who undergo general anaesthesia and might thus contribute to critical respiratory events in the post-anaesthesia care unit...

    Authors: Faraj K Alenezi, Khalid Alnababtah, Mohammed M Alqahtani, Lafi Olayan and Mohammed Alharbi
    Citation: Perioperative Medicine 2021 10:14
  40. Enhanced Recovery After Surgery (ERAS) programs have gained traction across US hospitals in the past two decades. Initially implemented for elective colorectal surgical procedures, ERAS has expanded to a varie...

    Authors: Sunitha M. Singh, Asha Liverpool, Jamie L. Romeiser, Julie Thacker, Tong J. Gan and Elliott Bennett-Guerrero
    Citation: Perioperative Medicine 2021 10:12
  41. Ambulatory surgical procedures continue to grow in relevance to perioperative medicine. Clinical studies have examined the use of systemic lidocaine as a component of multimodal analgesia in various surgeries ...

    Authors: Danielle Lovett-Carter, Mark C. Kendall, James Park, Anas Ibrahim-Hamdan, Susannah Crepet and Gildasio De Oliveira
    Citation: Perioperative Medicine 2021 10:11
  42. Intraoperative physiological monitoring generates a large quantity of time-series data that might be associated with postoperative outcomes. Using a deep learning model based on intraoperative time-series moni...

    Authors: Xu Zhao, Ke Liao, Wei Wang, Junmei Xu and Lingzhong Meng
    Citation: Perioperative Medicine 2021 10:8
  43. Although current guidelines make consensus recommendations for the early resumption of oral intake after surgery, a recent comprehensive meta-analysis failed to identify any patient-centered benefits. We hypot...

    Authors: Hong Pu, Philippa T. Heighes, Fiona Simpson, Yaoli Wang, Zeping Liang, Paul Wischmeyer, Thomas J. Hugh and Gordon S. Doig
    Citation: Perioperative Medicine 2021 10:10
  44. Consumer wrist-worn wearable activity monitors are widely available, low cost and are able to provide a direct measurement of several markers of physical activity. Despite this, there is limited data on their ...

    Authors: Laura Jones, Laura Tan, Suzanne Carey-Jones, Nathan Riddell, Richard Davies, Ashleigh Brownsdon, Mark Kelson, Rhys Williams-Thomas, Monica Busse, Michael M. Davies and Matt P. G. Morgan
    Citation: Perioperative Medicine 2021 10:9
  45. Health care workers (HCW) such as anesthesiologists, surgeons, and intensivists face high rates of exposure to SARS-CoV-2 through direct contact with COVID-19 patients. While there are initial reports of the p...

    Authors: Lillian R. Talbot, Jamie L. Romeiser, Eric D. Spitzer, Tong J. Gan, Sunitha M. Singh, Bettina C. Fries and Elliott Bennett-Guerrero
    Citation: Perioperative Medicine 2021 10:7

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