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  1. Pre-operative anaemia is associated with mortality and red blood cell (RBC) transfusion requirement after cardiac surgery. However, the effect on post-operative total morbidity burden (TMB) is unknown. We expl...

    Authors: Julie Sanders, Jackie A. Cooper, Daniel Farrar, Simon Braithwaite, Updeshbir Sandhu, Michael G. Mythen and Hugh E. Montgomery

    Citation: Perioperative Medicine 2017 6:1

    Content type: Research

    Published on:

  2. Several randomized controlled trials (RCTs) have demonstrated that intraoperative goal-directed fluid therapy (GDFT) can decrease postsurgical complications in patients undergoing major abdominal surgery. Howe...

    Authors: Marit Habicher, Felix Balzer, Viktor Mezger, Jennifer Niclas, Michael Müller, Carsten Perka, Michael Krämer and Michael Sander

    Citation: Perioperative Medicine 2016 5:31

    Content type: Research

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  3. Sarcopenia, or loss of skeletal muscle mass and quality, has been studied as part of aging and adverse health outcomes in elderly patients but has only recently been evaluated as a separate condition in cancer...

    Authors: Kimberly L. Mei, John A. Batsis, Jeannine B. Mills and Stefan D. Holubar

    Citation: Perioperative Medicine 2016 5:30

    Content type: Review

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  4. In this study, we examined the association between American Society of Anesthesiologists Physical Status (ASA PS) designation and 48-h mortality for both elective and emergent procedures in a large contemporar...

    Authors: Thomas J. Hopkins, Karthik Raghunathan, Atilio Barbeito, Mary Cooter, Mark Stafford-Smith, Rebecca Schroeder, Katherine Grichnik, Richard Gilbert and Solomon Aronson

    Citation: Perioperative Medicine 2016 5:29

    Content type: Research

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  5. The risk of spinal haematoma in patients receiving epidural catheters is estimated using routine coagulation tests, but guidelines are inconsistent in their recommendations on what to do when results indicate ...

    Authors: Owain Thomas, Hampus Rein, Karin Strandberg and Ulf Schött

    Citation: Perioperative Medicine 2016 5:28

    Content type: Research

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  6. Efforts to mitigate costs while improving surgical care quality have received much scrutiny. This includes the challenging issue of readmission subsequent to hospital discharge. Initiatives attempting to precl...

    Authors: Navid Alem, Joseph Rinehart, Brian Lee, Doug Merrill, Safa Sobhanie, Kyle Ahn, Ran Schwarzkopf, Maxime Cannesson and Zeev Kain

    Citation: Perioperative Medicine 2016 5:27

    Content type: Research

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  7. The 1st POQI Consensus Conference occurred in Durham, NC, on March 4–5, 2016, and was supported by the American Society of Enhanced Recovery (ASER) and Evidence-Based Perioperative Medicine (EBPOM). The confer...

    Authors: Timothy E. Miller, Andrew D. Shaw, Michael G. Mythen and Tong J Gan

    Citation: Perioperative Medicine 2016 5:26

    Content type: Editorial

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  8. Enhanced recovery may be viewed as a comprehensive approach to improving meaningful outcomes in patients undergoing major surgery. Evidence to support enhanced recovery pathways (ERPs) is strong in patients un...

    Authors: Robert H. Thiele, Karthik Raghunathan, C. S. Brudney, Dileep N. Lobo, Daniel Martin, Anthony Senagore, Maxime Cannesson, Tong Joo Gan, Michael Monty G. Mythen, Andrew D. Shaw and Timothy E. Miller

    Citation: Perioperative Medicine 2016 5:24

    Content type: Consensus statement

    Published on:

    The Correction to this article has been published in Perioperative Medicine 2018 7:5

  9. A1 Effects of enhanced recovery pathways on renal function

    Authors: Charles R. Horres, Mohamed A. Adam, Zhifei Sun, Julie K. Thacker, Timothy J. Miller, Stuart A. Grant, Jeffrey Huang, Kirstie McPherson, Sanjiv Patel, Su Cheen Ng, Denise Veelo, Bart Geerts, Monty Mythen, Su Cheen Ng, Mark Foulger, Tim Collins…

    Citation: Perioperative Medicine 2016 5(Suppl 1):21

    Content type: Meeting abstracts

    Published on:

    This article is part of a Supplement: Volume 5 Supplement 1

    The Erratum to this article has been published in Perioperative Medicine 2016 5:25

  10. Several studies have described hypercoagulability in neurosurgery with craniotomy for brain tumor resection. In this study, hydroxyethyl starch (HES) 130/0.42 was used for hemodynamic stabilization and initial...

    Authors: Caroline Ulfsdotter Nilsson, Karin Strandberg, Martin Engström and Peter Reinstrup

    Citation: Perioperative Medicine 2016 5:20

    Content type: Research

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  11. Postoperative pulmonary complications in orthopedic surgery patients have been associated with worse clinical outcomes. Identifying patients with respiratory risk factors requiring enhanced monitoring and mana...

    Authors: Roman Melamed, Lori L. Boland, James P. Normington, Rebecca M. Prenevost, Lindsay Y. Hur, Leslie F. Maynard, Molly A. McNaughton, Tyler G. Kinzy, Adnan Masood, Mehdi Dastrange and Joseph A. Huguelet

    Citation: Perioperative Medicine 2016 5:19

    Content type: Research

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  12. Preoperative assessment of functional capacity is necessary to direct decisions regarding cardiac evaluation and may help identify patients at high risk for perioperative complications. Patient self-triage reg...

    Authors: John Whittemore Stokes, Jonathan Porter Wanderer and Matthew David McEvoy

    Citation: Perioperative Medicine 2016 5:18

    Content type: Research

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  13. Despite numerous interventions promulgated by the Surgical Care Improve Project (SCIP) and other organizations, surgical site infection (SSI) continues to be a significant medical problem. DFA-02 is a novel bi...

    Authors: Elliott Bennett-Guerrero, Harold S. Minkowitz, Alvaro M. Segura-Vasi, Jorge E. Marcet, Jennifer A. White, G Ralph Corey and Kent S. Allenby

    Citation: Perioperative Medicine 2016 5:17

    Content type: Research

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  14. Surgical ambition is rising, with the Royal College of Surgeons reporting an increase in the number of procedures by a million over the past decade (Royal College of Surgeons. Surgery and the NHS in Numbers. A...

    Authors: Ramai Santhirapala and Ramani Moonesinghe

    Citation: Perioperative Medicine 2016 5:16

    Content type: Commentary

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  15. Fluid resuscitation is a cornerstone of intensive care treatment, yet there is a lack of agreement on how various types of fluids should be used in critically ill patients with different disease states. Theref...

    Authors: Timothy E. Miller, Martin Bunke, Paul Nisbet and Charles S. Brudney

    Citation: Perioperative Medicine 2016 5:15

    Content type: Research

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  16. Pre-operative antibody levels have been shown to be inversely related to development of post-operative complications. Staphylococcal infection is a major source of morbidity following surgery.

    Authors: Sarka Moravcova, Bonnie Kyle, Hilary Shanahan, Savvas Giannaris, Andrew Smith and Colin Hamilton-Davies

    Citation: Perioperative Medicine 2016 5:13

    Content type: Research

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  17. Anaesthesia is frequently complicated by intraoperative hypotension (IOH) in the elderly, and this is associated with adverse outcome. The definition of IOH is controversial, and although management guidelines...

    Authors: Alex Wickham, David Highton and Daniel Martin

    Citation: Perioperative Medicine 2016 5:12

    Content type: Research

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  18. In-hospital falls may result in serious clinical adverse consequences, but the effects of anesthesia in the occurrence of postoperative falls are still undetermined. Anesthesia may theoretically cause postoper...

    Authors: Chen-Fuh Lam, Shiu-Ying Hsieh, Jen-Hung Wang, Hui-Shan Pan, Xiu-Zhu Liu, Yu-Ching Ho and Tsung-Ying Chen

    Citation: Perioperative Medicine 2016 5:11

    Content type: Research

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  19. Postoperative pulmonary complications (PPC) are an under-reported but major cause of perioperative morbidity and mortality. The aim of this prospective, contemporary, multicentre cohort study of unselected pat...

    Authors: Kamlesh Patel, Fatemeh Hadian, Aysha Ali, Graham Broadley, Kate Evans, Claire Horder, Marianne Johnstone, Fiona Langlands, Jake Matthews, Prithish Narayan, Priya Rallon, Charlotte Roberts, Sonali Shah and Ravinder Vohra

    Citation: Perioperative Medicine 2016 5:10

    Content type: Research

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  20. Oral antiseptics reduce nosocomial infections and ventilator-associated pneumonia in critically ill medical and surgical patients intubated for prolonged periods. However, the role of oral antiseptics given be...

    Authors: Philip Spreadborough, Sarah Lort, Sandro Pasquali, Matthew Popplewell, Andrew Owen, Irene Kreis, Olga Tucker and Ravinder S Vohra

    Citation: Perioperative Medicine 2016 5:6

    Content type: Research

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  21. Explicit consideration of anticipated regret is not part of the standard shared decision-making protocols. This pilot study aimed to compare decisions about a hypothetical surgery for breast cancer and examine...

    Authors: Rebecca M. Speck, Mark D. Neuman, Kimberly S. Resnick, Barbara A. Mellers and Lee A. Fleisher

    Citation: Perioperative Medicine 2016 5:5

    Content type: Research

    Published on:

  22. International experience and evidence-based practices have shown that reduction in variability through use of protocolized perioperative care improves surgical outcomes and reduces costs to patients and health...

    Authors: Ruchir Gupta and Roy Soto

    Citation: Perioperative Medicine 2016 5:4

    Content type: Editorial

    Published on:

    The Erratum to this article has been published in Perioperative Medicine 2016 5:9

  23. A major restructuring of perioperative care delivery is required to reduce cost while improving patient outcomes. In a test implementation of this notion, we developed and implemented a perioperative consult s...

    Authors: Matthew D. McEvoy, Jonathan P. Wanderer, Adam B. King, Timothy M. Geiger, Vikram Tiwari, Maxim Terekhov, Jesse M. Ehrenfeld, William R. Furman, Lorri A. Lee and Warren S. Sandberg

    Citation: Perioperative Medicine 2016 5:3

    Content type: Research

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  24. The advancement of perioperative medicine is leading to greater diversity in development of pre-surgical interventions, implemented to reduce patient surgical risk and enhance post-surgical recovery. Of these ...

    Authors: Matthew Weston, Kathryn L Weston, James M. Prentis and Chris P Snowden

    Citation: Perioperative Medicine 2016 5:2

    Content type: Opinion

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  25. Excessive or inadequate intravenous fluid given in the perioperative period can affect outcomes. A number of guidelines exist but these can conflict with the entrenched practice, evidence base and prescriber k...

    Authors: Benjamin Harris, Christian Schopflin, Clare Khaghani and Mark Edwards

    Citation: Perioperative Medicine 2015 4:15

    Content type: Research

    Published on:

  26. Despite existing evidence and guidelines advocating for appropriate risk stratification, ambulatory surgery in low-risk patients continues to be accompanied by a battery of routine tests prior to surgery. Usin...

    Authors: Onyi C. Onuoha, Michael B. Hatch, Todd A. Miano and Lee A. Fleisher

    Citation: Perioperative Medicine 2015 4:14

    Content type: Research

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  27. The use of cardiac output monitoring to guide intra-venous fluid and inotropic therapies may improve peri-operative outcomes, but uncertainty exists regarding clinical effectiveness and robust cost-effectivene...

    Authors: Zia Sadique, David A. Harrison, Richard Grieve, Kathryn M. Rowan and Rupert M. Pearse

    Citation: Perioperative Medicine 2015 4:13

    Content type: Research

    Published on:

  28. Preventable postsurgical complications are increasingly recognized as a major clinical and economic burden. A recent meta-analysis showed a 17–29 % decrease in postoperative morbidity with goal-directed fluid ...

    Authors: Frederic Michard, William K. Mountford, Michelle R. Krukas, Frank R. Ernst and Sandy L. Fogel

    Citation: Perioperative Medicine 2015 4:11

    Content type: Research

    Published on:

  29. Currently, there is no standardised tool used to capture morbidity following abdominal aortic aneurysm (AAA) repair. The aim of this prospective observational study was to validate the Postoperative Morbidity ...

    Authors: Ben A. Goodman, Alan M. Batterham, Elke Kothmann, Louise Cawthorn, David Yates, Helen Melsom, Karen Kerr and Gerard R. Danjoux

    Citation: Perioperative Medicine 2015 4:10

    Content type: Research

    Published on:

  30. The European Medicines Agency does not recommend the use of hydroxyethyl starch-based volume replacement solutions in critically ill patients due to an increased risk of renal failure. However, this recommenda...

    Authors: N. Li, S. Statkevicius, B. Asgeirsson and U. Schött

    Citation: Perioperative Medicine 2015 4:9

    Content type: Research

    Published on:

  31. The use of cardiac output monitoring may improve patient outcomes after major surgery. However, little is known about the use of this technology across nations.

    Authors: Tahania Ahmad, Christian M. Beilstein, Cesar Aldecoa, Rui P. Moreno, Zsolt Molnár, Vesna Novak-Jankovic, Christoph K. Hofer, Michael Sander, Andrew Rhodes and Rupert M. Pearse

    Citation: Perioperative Medicine 2015 4:8

    Content type: Research

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  32. Perioperative goal-directed fluid therapy (GDFT) may improve outcome after high-risk surgery. Minimal invasive measurement of stroke volume variation (SVV) has been recommended to guide fluid therapy. We inten...

    Authors: Ib Jammer, Mari Tuovila and Atle Ulvik

    Citation: Perioperative Medicine 2015 4:6

    Content type: Research

    Published on:

  33. Appropriately timed patient discharge is essential for optimal patient care and efficient hospital functioning. The post-operative morbidity survey (POMS) is the only validated prospective method of measuring ...

    Authors: Elizabeth Ashby, Claire Matejowsky, Michael G Mythen, Fares S Haddad and Michael PW Grocott

    Citation: Perioperative Medicine 2015 4:5

    Content type: Research

    Published on:

  34. Patient satisfaction is an important metric of health-care quality. Accidental awareness under general anaesthesia (AAGA) is a serious complication of anaesthesia care which may go unrecognised in the immediat...

    Authors: Suneetha Ramani Moonesinghe, Eleanor Mary Kate Walker and Madeline Bell

    Citation: Perioperative Medicine 2015 4:4

    Content type: Research

    Published on:

  35. Perioperative fluid therapy remains a highly debated topic. Its purpose is to maintain or restore effective circulating blood volume during the immediate perioperative period. Maintaining effective circulating...

    Authors: Lais Helena Camacho Navarro, Joshua A Bloomstone, Jose Otavio Costa Auler Jr, Maxime Cannesson, Giorgio Della Rocca, Tong J Gan, Michael Kinsky, Sheldon Magder, Timothy E Miller, Monty Mythen, Azriel Perel, Daniel A Reuter, Michael R Pinsky and George C Kramer

    Citation: Perioperative Medicine 2015 4:3

    Content type: Consensus statement

    Published on:

  36. Several plasma volume expander alternatives exist to enhance intravascular volume status in patients undergoing surgery. The optimal intravascular volume expander in the perioperative setting is currently unkn...

    Authors: Raquel R Bartz, William D White and Tong J Gan

    Citation: Perioperative Medicine 2015 4:2

    Content type: Research

    Published on:

  37. Goal-directed therapy (GDT) utilizes monitoring techniques to help guide clinicians with administering fluids, vasopressors, inotropes, or other treatments to patients in various clinical settings. Multiple st...

    Authors: Jason B O’Neal and Andrew D Shaw

    Citation: Perioperative Medicine 2015 4:1

    Content type: Editorial

    Published on:

  38. The benefit of the post-anaesthesia care unit (PACU) with respect to an early detection of postoperative complications is beyond dispute. From a patient perspective, prevention and optimal management of pain, ...

    Authors: Michael T Ganter, Stephan Blumenthal, Seraina Dübendorfer, Simone Brunnschweiler, Tim Hofer, Richard Klaghofer, Andreas Zollinger and Christoph K Hofer

    Citation: Perioperative Medicine 2014 3:10

    Content type: Research

    Published on:

  39. In particular surgical conditions, a balanced anesthesia with a high-antinociceptive contribution is required. This may induce cardiovascular impairment and thus compromise tissue oxygenation. In this prospect...

    Authors: Jaap Jan Vos, Marieke Poterman, Laura N Hannivoort, Victor W Renardel De Lavalette, Michel MRF Struys, Thomas WL Scheeren and Alain F Kalmar

    Citation: Perioperative Medicine 2014 3:9

    Content type: Research

    Published on:

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