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  1. Hyponatraemia, defined as a serum sodium [Na] concentration below 135 mmol/L, is common following surgery. As inpatient peri-operative stays shorten, there is a need to recognise pre-operative risk factors for...

    Authors: Emma Cunningham, Nicola Gallagher, Paul Hamilton, Leeann Bryce and David Beverland

    Citation: Perioperative Medicine 2021 10:25

    Content type: Research

    Published on:

  2. Emergency laparotomy carries a significant risk profile around the time of surgery. This research aimed to establish the feasibility of recruitment to a study using validated scoring tools to assess complicati...

    Authors: D. I. Saunders, R. C. F. Sinclair, B. Griffiths, E. Pugh, D. Harji, B. Salas, H. Reed and C. Scott

    Citation: Perioperative Medicine 2021 10:22

    Content type: Research

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  3. Acute ischemic thromboembolic stroke is one of the most feared complications of atrial fibrillation (AF), and the risk increases with higher CHA2DS2-VASc scores. Postoperative atrial fibrillation (POAF) is com...

    Authors: Jennifer Mardini, Melanio Bruceta, William Parrella-O’Donnell and Kunal Karamchandani

    Citation: Perioperative Medicine 2021 10:17

    Content type: Case Study

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  4. Postoperative heart failure (PHF) is the main cause for mortality after cardiac surgery but unbiased evaluation of PHF is difficult. We investigated the utility of postoperative NT-proBNP as an objective marke...

    Authors: Huiqi Jiang, Jonas Holm, Örjan Friberg, Farkas Vanky, Mårten Vidlund, Bashir Tajik, Yanqi Yang and Rolf Svedjeholm

    Citation: Perioperative Medicine 2021 10:21

    Content type: Research

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  5. Evidence suggests that unhealthy lifestyle behaviours are modifiable risk factors for postoperative complications. Digital behaviour change interventions (DBCIs), for instance text messaging programs and smart...

    Authors: Katarina Åsberg and Marcus Bendtsen

    Citation: Perioperative Medicine 2021 10:18

    Content type: Review

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  6. The EMPOWER trial aimed to assess the effects of a 9-week exercise prehabilitation programme on physical fitness compared with a usual care control group. Secondary aims were to investigate the effect of (1) t...

    Authors: Lisa Loughney, Malcolm A. West, Helen Moyses, Andrew Bates, Graham J. Kemp, Lesley Hawkins, Judit Varkonyi-Sepp, Shaunna Burke, Christopher P. Barben, Peter M. Calverley, Trevor Cox, Daniel H. Palmer, Michael G. Mythen, Michael P. W. Grocott and Sandy Jack

    Citation: Perioperative Medicine 2021 10:23

    Content type: Research

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  7. Group education is increasing in popularity as a means of preparing patients for surgery. In recent years, these ‘surgery schools’ have evolved from primarily informing patients of what to expect before and af...

    Authors: I. Fecher-Jones, C. Grimmett, F. J. Carter, D. H. Conway, D. Z. H. Levett and J. A. Moore

    Citation: Perioperative Medicine 2021 10:20

    Content type: Research

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  8. The superiority of either the traditional or Stewart based approach to acid-base balance has focused primarily on analyzing metabolic acidemia, with little attention given to patients with neutral pH. In this ...

    Authors: Joost W. Janssen, Joris M. K. van Fessem, Tijmen Ris, Robert Jan Stolker and Markus Klimek

    Citation: Perioperative Medicine 2021 10:15

    Content type: Research

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  9. Carbohydrate-containing drinks (CCD) are administered preoperatively in most enhanced recovery after surgery (ERAS) programs. It is not known which types of CCDs are used, e.g., simple vs. complex carbohydrate...

    Authors: Sunitha M. Singh, Asha Liverpool, Jamie L. Romeiser, Joshua D. Miller, Julie Thacker, Tong J. Gan and Elliott Bennett-Guerrero

    Citation: Perioperative Medicine 2021 10:19

    Content type: Research

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  10. Postoperative acute kidney injury (PO-AKI) is a leading cause of short- and long-term morbidity and mortality, as well as progression to chronic kidney disease (CKD). The aim of this study was to explore the p...

    Authors: Gianluca Villa, Silvia De Rosa, Caterina Scirè Calabrisotto, Alessandro Nerini, Thomas Saitta, Dario Degl’Innocenti, Laura Paparella, Vittorio Bocciero, Marco Allinovi, Angelo R. De Gaudio, Marlies Ostermann and Stefano Romagnoli

    Citation: Perioperative Medicine 2021 10:13

    Content type: Research

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  11. The safety of perioperative intravenous hydroxyethyl starch (HES) products, specifically HES 130/0.4, continues to be the source of much debate. The aim of this meta-analysis was to update the existing evidenc...

    Authors: Yi Xu, Siying Wang, Leilei He, Hong Yu and Hai Yu

    Citation: Perioperative Medicine 2021 10:16

    Content type: Review

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  12. Inadequate neuromuscular recovery might impair pulmonary function among adult patients who undergo general anaesthesia and might thus contribute to critical respiratory events in the post-anaesthesia care unit...

    Authors: Faraj K Alenezi, Khalid Alnababtah, Mohammed M Alqahtani, Lafi Olayan and Mohammed Alharbi

    Citation: Perioperative Medicine 2021 10:14

    Content type: Research

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  13. Enhanced Recovery After Surgery (ERAS) programs have gained traction across US hospitals in the past two decades. Initially implemented for elective colorectal surgical procedures, ERAS has expanded to a varie...

    Authors: Sunitha M. Singh, Asha Liverpool, Jamie L. Romeiser, Julie Thacker, Tong J. Gan and Elliott Bennett-Guerrero

    Citation: Perioperative Medicine 2021 10:12

    Content type: Research

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  14. Ambulatory surgical procedures continue to grow in relevance to perioperative medicine. Clinical studies have examined the use of systemic lidocaine as a component of multimodal analgesia in various surgeries ...

    Authors: Danielle Lovett-Carter, Mark C. Kendall, James Park, Anas Ibrahim-Hamdan, Susannah Crepet and Gildasio De Oliveira

    Citation: Perioperative Medicine 2021 10:11

    Content type: Research

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  15. Intraoperative physiological monitoring generates a large quantity of time-series data that might be associated with postoperative outcomes. Using a deep learning model based on intraoperative time-series moni...

    Authors: Xu Zhao, Ke Liao, Wei Wang, Junmei Xu and Lingzhong Meng

    Citation: Perioperative Medicine 2021 10:8

    Content type: Research

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  16. Although current guidelines make consensus recommendations for the early resumption of oral intake after surgery, a recent comprehensive meta-analysis failed to identify any patient-centered benefits. We hypot...

    Authors: Hong Pu, Philippa T. Heighes, Fiona Simpson, Yaoli Wang, Zeping Liang, Paul Wischmeyer, Thomas J. Hugh and Gordon S. Doig

    Citation: Perioperative Medicine 2021 10:10

    Content type: Research

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  17. Consumer wrist-worn wearable activity monitors are widely available, low cost and are able to provide a direct measurement of several markers of physical activity. Despite this, there is limited data on their ...

    Authors: Laura Jones, Laura Tan, Suzanne Carey-Jones, Nathan Riddell, Richard Davies, Ashleigh Brownsdon, Mark Kelson, Rhys Williams-Thomas, Monica Busse, Michael M. Davies and Matt P. G. Morgan

    Citation: Perioperative Medicine 2021 10:9

    Content type: Research

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  18. Health care workers (HCW) such as anesthesiologists, surgeons, and intensivists face high rates of exposure to SARS-CoV-2 through direct contact with COVID-19 patients. While there are initial reports of the p...

    Authors: Lillian R. Talbot, Jamie L. Romeiser, Eric D. Spitzer, Tong J. Gan, Sunitha M. Singh, Bettina C. Fries and Elliott Bennett-Guerrero

    Citation: Perioperative Medicine 2021 10:7

    Content type: Research

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  19. Chronic pain after breast surgery (CPBS) has a disabling impact on postoperative health status. Mainly because of the lack of a clear definition, inconsistency does exist in the literature concerning both the ...

    Authors: Gianluca Villa, Raffaele Mandarano, Caterina Scirè-Calabrisotto, Valeria Rizzelli, Martina Del Duca, Diego Pomarè Montin, Laura Paparella, A. Raffaele De Gaudio and Stefano Romagnoli

    Citation: Perioperative Medicine 2021 10:6

    Content type: Research

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  20. Despite improvements in perioperative care, major abdominal surgery continues to be associated with significant perioperative morbidity. Accurate preoperative risk stratification and optimisation (prehabilitat...

    Authors: Laura van Wijk, Lizzel van der Snee, Carlijn I. Buis, Judith E. K. R. Hentzen, Marjolein E. Haveman and Joost M. Klaase

    Citation: Perioperative Medicine 2021 10:5

    Content type: Research

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  21. Although postoperative delirium is a frequent complication of surgery, little is known about risk factors for delirium occurring in the post-anaesthesia care unit (PACU). The aim of this study was to determine...

    Authors: Jiayi Wu, Shaojie Gao, Shuang Zhang, Yao Yu, Shangkun Liu, Zhiguo Zhang and Wei Mei

    Citation: Perioperative Medicine 2021 10:3

    Content type: Research

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  22. Assessing the risk of post-surgical mortality is a key component of pre-surgical planning. The Surgical Outcome Risk Tool (SORT) uses pre-operative variables to predict 30-day mortality. The aim of this study ...

    Authors: K. Oakland, D. Cosentino, T. Cross, C. Bucknall, S. Dorudi and D. Walker

    Citation: Perioperative Medicine 2021 10:4

    Content type: Research

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  23. The preoperative evaluation and risk assessment has always been a critical aspect of safe surgical practice, and in the midst of the SARS-CoV-2 pandemic, it has become even more crucial to patient safety. Emer...

    Authors: Naomi Bui, Mareli Coetzer, Katie J. Schenning and Avital Y. O’Glasser

    Citation: Perioperative Medicine 2021 10:1

    Content type: Commentary

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  24. Knowledge of risk factors for postoperative urinary retention may guide appropriate and timely urinary catheterization. We aimed to determine independent risk factors for postoperative urinary catheterization ...

    Authors: Tammo A. Brouwer, E. N. van Roon, P. F. W. M. Rosier, C. J. Kalkman and N. Veeger

    Citation: Perioperative Medicine 2021 10:2

    Content type: Research

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  25. A maladaptive response to surgical stress might lead to postoperative complications. A multidisciplinary approach aimed at controlling the surgical stress response may reduce procedural complications and impro...

    Authors: Gianluca Villa, Iacopo Lanini, Timothy Amass, Vittorio Bocciero, Caterina Scirè Calabrisotto, Cosimo Chelazzi, Stefano Romagnoli, A. Raffaele De Gaudio and Rosapia Lauro Grotto

    Citation: Perioperative Medicine 2020 9:38

    Content type: Review

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  26. Anesthetic care in patients undergoing thoracic surgery presents specific challenges that necessitate standardized, multidisciplionary, and continuously updated guidelines for perioperative care.

    Authors: Federico Piccioni, Andrea Droghetti, Alessandro Bertani, Cecilia Coccia, Antonio Corcione, Angelo Guido Corsico, Roberto Crisci, Carlo Curcio, Carlo Del Naja, Paolo Feltracco, Diego Fontana, Alessandro Gonfiotti, Camillo Lopez, Domenico Massullo, Mario Nosotti, Riccardo Ragazzi…

    Citation: Perioperative Medicine 2020 9:37

    Content type: Consensus

    Published on:

  27. Safe and accurate pre-procedural assessment of cardiovascular anatomy, physiology, and pathophysiology prior to TAVR procedures can mean the difference between success and catastrophic failure. It is imperativ...

    Authors: Tjörvi E. Perry, Stephen A. George, Belinda Lee, Joyce Wahr, Darrell Randle and Garðar Sigurðsson

    Citation: Perioperative Medicine 2020 9:36

    Content type: Review

    Published on:

  28. Increasing numbers of patients receiving oral anticoagulants are undergoing elective surgery. Low molecular weight heparin (LMWH) is frequently applied as bridging therapy during perioperative interruption of ...

    Authors: J. F. Lock, L. Ungeheuer, P. Borst, J. Swol, S. Löb, E. M. Brede, D. Röder, B. Lengenfelder, K. Sauer and C.-T. Germer

    Citation: Perioperative Medicine 2020 9:39

    Content type: Research

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  29. Recent literature has demonstrated that hemodynamic instability in the intraoperative period places patients at risk of poor outcomes. Furthermore, recent studies have reported that stroke volume optimization ...

    Authors: Matthew D. McEvoy, Jonathan P. Wanderer, Yaping Shi, Krishnan S. Ramanujan, Timothy M. Geiger, Matthew S. Shotwell, Andrew D. Shaw, Alexander T. Hawkins, Barbara J. Martin, Michael G. Mythen and Warren S. Sandberg

    Citation: Perioperative Medicine 2020 9:35

    Content type: Research

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  30. A successful anesthesia pre-assessment clinic needs to identify patients who need further testing, evaluation, and optimization prior to the day of surgery to avoid delays and cancelations. Although the ASA Ph...

    Authors: Amr E. Abouleish, Sandhya R. Vinta, Sarah M. Shabot, Nikul V. Patel, Erin E. Hurwitz, Partha Krishnamurthy and Michelle Simon

    Citation: Perioperative Medicine 2020 9:34

    Content type: Research

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  31. An ageing population has resulted in a rise in the number of hip and knee replacement surgeries in the UK. The pre-operative pathway is plagued with issues causing long delays and cancellations. Virtual health...

    Authors: Faraz Sharif, Ammar Rahman, Emma Tonner, Hanad Ahmed, Iqraa Haq, Rami Abbass, Shad Asinger and Magda Sbai

    Citation: Perioperative Medicine 2020 9:33

    Content type: Research

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  32. Postdural puncture headache is one of the complications following spinal anesthesia and accidental dural puncture. Several modifiable risk factors contribute to the development of headache after lumbar punctur...

    Authors: Bedilu Girma Weji, Mohammed Suleiman Obsa, Kidest Getu Melese and Gedion Asnake Azeze

    Citation: Perioperative Medicine 2020 9:32

    Content type: Research

    Published on:

  33. Anesthetic care in patients undergoing thoracic surgery presents specific challenges that require a multidisciplinary approach to management. There remains a need for standardized, evidence-based, continuously...

    Authors: Federico Piccioni, Andrea Droghetti, Alessandro Bertani, Cecilia Coccia, Antonio Corcione, Angelo Guido Corsico, Roberto Crisci, Carlo Curcio, Carlo Del Naja, Paolo Feltracco, Diego Fontana, Alessandro Gonfiotti, Camillo Lopez, Domenico Massullo, Mario Nosotti, Riccardo Ragazzi…

    Citation: Perioperative Medicine 2020 9:31

    Content type: Consensus

    Published on:

  34. Perioperative goal-directed haemodynamic therapy (GDHT), defined as the administration of fluids with or without inotropes or vasoactive agents against explicit measured goals to augment blood flow, has been e...

    Authors: Ahilanandan Dushianthan, Martin Knight, Peter Russell and Michael PW Grocott

    Citation: Perioperative Medicine 2020 9:30

    Content type: Research

    Published on:

  35. Small randomized trials of early postoperative oral nutritional supplementation (ONS) suggest various health benefits following colorectal surgery (CRS). However, real-world evidence of the impact of early ONS...

    Authors: David G. A. Williams, Tetsu Ohnuma, Vijay Krishnamoorthy, Karthik Raghunathan, Suela Sulo, Bridget A. Cassady, Refaat Hegazi and Paul E. Wischmeyer

    Citation: Perioperative Medicine 2020 9:29

    Content type: Research

    Published on:

  36. Individual surgical risk assessment (ISRA) enhances patient care experience and outcomes by informing shared decision-making, strengthening the consent process, and supporting clinical management. Neither the ...

    Authors: Joshua A. Bloomstone, Benjamin T. Houseman, Evora Vicents Sande, Ann Brantley, Jessica Curran, Gerald A. Maccioli, Tania Haddad, James Steinshouer, David Walker and Ramani Moonesinghe

    Citation: Perioperative Medicine 2020 9:28

    Content type: Research

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  37. Multicomponent peri-operative interventions offer to accelerate patient recovery and improve cost-effectiveness. The recent National Institute of Health Research-commissioned evidence synthesis review by Nunns...

    Authors: Michael Nunns, Joseph B. John, John S. McGrath, Liz Shaw, Simon Briscoe, Jo Thompson Coon, Anthony Hemsley, Christopher J. Lovegrove, David Thomas, Michael G. Mythen and Rob Anderson

    Citation: Perioperative Medicine 2020 9:27

    Content type: Editorial

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  38. Hypotension following major abdominal surgery is common, and once hypovolaemia has been optimally treated, is often due to vasodilation which can be treated with vasopressor infusions. There is unpredictabilit...

    Authors: Michèle Bossy, Molly Nyman, Thumuluru Kavitha Madhuri, Anil Tailor, Jayanta Chatterjee, Simon Butler-Manuel, Patricia Ellis, Aarne Feldheiser and Ben Creagh-Brown

    Citation: Perioperative Medicine 2020 9:26

    Content type: Research

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  39. Advances in healthcare delivery have allowed for the increase in the number of ambulatory surgery procedures performed in Canada. Despite these advances, patients return to hospital following discharge. Howeve...

    Authors: Monakshi Sawhney, David H. Goldstein, Xuejiao Wei, Genevieve C. Pare, Louie Wang and Elizabeth G. VanDenKerkhof

    Citation: Perioperative Medicine 2020 9:25

    Content type: Research

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  40. Individuals with obesity frequently present for anaesthesia and surgery. Good communication during the preoperative consultation can optimise the provision of relevant health information and guide improvement ...

    Authors: Anthony Hodsdon, Natalie Anne Smith and David A. Story

    Citation: Perioperative Medicine 2020 9:24

    Content type: Review

    Published on:

  41. Gastrointestinal cancer surgery continues to be a significant cause of postoperative complications and mortality in high-risk patients. It is crucial to identify these patients. Our study aimed to evaluate the...

    Authors: Antero Fernandes, Jéssica Rodrigues, Luís Antunes, Patrícia Lages, Carla Salomé Santos, Daniel Moreira-Gonçalves, Rafael S. Costa, Joaquim Abreu Sousa, Mário Dinis-Ribeiro and Lúcio Lara Santos

    Citation: Perioperative Medicine 2020 9:23

    Content type: Research

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  42. An elevated cardiac troponin level after noncardiac surgery is associated with both morbidity and mortality. Guidelines suggest routine troponin monitoring in high-risk patients. We implemented a dedicated ane...

    Authors: Annemarie Akkermans, Lisette M. Vernooij, Wilton A. van Klei and Judith A. van Waes

    Citation: Perioperative Medicine 2020 9:22

    Content type: Research

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  43. Evidence-based perioperative analgesia is an important tactic for reducing patient exposure to opioids in the perioperative period and potentially preventing new persistent opioid use.

    Authors: Ankit Sarin, Elizabeth Lancaster, Lee-lynn Chen, Sima Porten, Lee-may Chen, Jeanette Lager and Elizabeth Wick

    Citation: Perioperative Medicine 2020 9:21

    Content type: Research

    Published on:

  44. Multiple tools exist estimating perioperative risk. With an ageing surgical demographic, frailty is becoming an increasingly important concept in perioperative medicine due to its association with adverse post...

    Authors: Simon J. G. Richards, Pippa M. Jerram, Christian Brett, Michelle Falloon and Frank A. Frizelle

    Citation: Perioperative Medicine 2020 9:20

    Content type: Research

    Published on:

  45. Post-operative pain management should ideally be optimized to ensure patient’s mobilization and ability to partake in effective pulmonary exercises for patient’s early recovery. Opioids have traditionally been...

    Authors: Sushan Gupta, Avani Mohta and Vijaya Gottumukkala

    Citation: Perioperative Medicine 2020 9:16

    Content type: Commentary

    Published on:

  46. Intravenous iron is increasingly used prior to surgery for colorectal cancer (CRC) to correct iron deficiency anaemia and reduce blood transfusion. Its utility in functional iron deficiency (FID) or anaemia of...

    Authors: Stephen T. McSorley, John H. Anderson, Thomas Whittle, Campbell S. Roxburgh, Paul G. Horgan, Donald C. McMillan and Colin W. Steele

    Citation: Perioperative Medicine 2020 9:17

    Content type: Research

    Published on:

  47. The use of preoperative cardiopulmonary exercise testing (CPET) to evaluate the risk of adverse perioperative outcomes is increasingly prevalent. CPET-derived information enables personalised perioperative car...

    Authors: G. Thomas, M. A. West, M. Browning, G. Minto, M. Swart, K. Richardson, L. McGarrity, S. Jack, M. P. W. Grocott and D. Z. H. Levett

    Citation: Perioperative Medicine 2020 9:18

    Content type: Research

    Published on:

  48. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Jean-Francois Bonnet, Eleanor Buggy, Barbara Cusack, Aislinn Sherwin, Tom Wall, Maria Fitzgibbon and Donal J. Buggy

    Citation: Perioperative Medicine 2020 9:19

    Content type: Correction

    Published on:

    The original article was published in Perioperative Medicine 2020 9:9

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