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Table 1 Comparison of baseline and intraoperative data between the two groups

From: Effects of short-term preoperative intranasal dexmedetomidine plus conventional treatment on delirium following cardiac surgery in patients with sleep disorders

Characteristic

Group A (n=50)

Group B (n=50)

P Value

Age (y)

68.1(4.3)

66.9(3.4)

0.120

BMI (kg/m2)

23.8(3.4)

23.6 (2.5)

0.745

Gender (female), n (%)

22(44.0)

19 (38.0)

0.542

PSQI0 (median, IQR)

12.0 (10.8,14.0)

11.5(9.0,13.0)

0.071

Preoperative anxiety (SAS≥55), n (%)

15(30)

18(36)

0.523

Preintervention clinical insomnia (ISI≥15), n (%)

16 (32)

18 (36)

0.673

EF (%)

63.3 (6.3)

62.9 (7.3)

0.759

Smoking, n (%)

8(16.0)

7 (14.0)

0.779

Hypertension, n (%)

29(58.0)

27 (54.0)

0.687

Diabetes, n (%)

10(20.0)

10(20.0)

-

Anaemia, n (%)

10(20.0)

9 (18.0)

0.799

MCI, n (%)

8(16.0)

6 (12.0)

0.564

Type of procedure, n (%)

 Off-pump CABG, n (%)

14(28.0)

21(42.0)

0.142

 Valve or aortic root surgery, n (%)

36(72.0)

29(58.0)

 

Length of surgery (median, IQR, min)

292.5(250.0,332.5)

300.0(253.8,345.0)

0.684

Anaesthetic duration (median, IQR, min)

327.5(295.0, 397.0)

357.5(307.5, 401.3)

0.261

Sufentanil (median, IQR, µg)

361.0 (321.0, 395.0)

361.5 (341.0,407.5)

0.569

Propofol (median, IQR, mg)

1155.0(1012.0, 1337.0)

1200.0(1015.8,1463.0)

0.530

Serious event

 Serious hypotension, n (%)

5(10.0)

6(12.0)

0.749

 Cardiac arrest, n (%)

0 (0)

1 (1.1)

>0.999*

 Heavy bleeding, n (%)

0 (0)

0 (0)

-

  1. Data are presented as the median (interquartile range) or n (%)
  2. BMI Body mass index, PSQI0 baseline Pittsburgh sleep quality index, IQR interquartile range, SAS Self-Rating Anxiety Scale, ISI Insomnia severity index, EF Ejection fraction, MCI Mild cognitive impairment, CABG Coronary artery bypass grafting
  3. *Fisher’s exact test