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Featured article

A randomized, double-blind, placebo controlled safety, tolerability, and pharmacokinetic dose escalation study of a gentamicin vancomycin gel in patients undergoing colorectal surgery by E.Bennett-Guerrero et al.

Despite numerous interventions promoted by the Surgical Care Improve Project (SCIP) and other organizations, surgical site infection remains a significant medical problem. This study tested the safety and tolerability of DFA-02, a novel bioresorbable modified-release gel consisting of both gentamicin (16.8 mg/mL) and vancomycin (18.8 mg/mL), during surgical incision closure for the prevention of surgical site infection.

Society affiliation

Perioperative Medicine is the official journal of the American Society for Enhanced Recovery (ASER).

ASER is a nonprofit organization with an international membership, which is dedicated to promote the practice of enhanced recovery in the perioperative patients through education and research. The ASER Mission is to advance the practice of perioperative enhanced recovery, to contribute to its growth and influences, by fostering and encouraging research, education, public policies and programs and scientific progress.

For more information, please see the ASER website.

Editors' profiles

Dr Mark A Hamilton, Editor-in-Chief

Dr Mark Hamilton is Consultant and Honorary Senior Lecturer in Anaesthesia and Intensive Care Medicine at St George's Hospital, London. He trained and has worked in London for the past 20 years, and is currently undertaking a postgraduate degree in preoperative physiological testing at University College London. His research interests include haemodynamic optimisation, tissue oxygenation, nutrition and care of high risk surgical patients. His clinical interests include preoperative testing and anaesthesia.

Care of the surgical patient is increasingly recognised to rely on a coordinated approach to healthcare by a multidisciplinary team. Perioperative Medicine brings together the best research from all of these fields and applies it to the care of patients undergoing surgery to help healthcare providers improve their patients' outcomes.

Prof Michael (Monty) G Mythen, Editor-in-Chief

Prof Mythen is the Smiths Medical Professor of Anaesthesia and Critical Care at University College London (UCL). Director of The UCL Discovery Lab at The London 2012 Olympic legacy Institute of Sport Exercise and Health. Before returning to the UK, he was an assistant Professor at Duke University Medical Centre and acting Chief of Critical Care in the Department of Anesthesiology.

He is also an Elected Council Member of the Royal College of Anaesthetists and Leads their Perioperative Medicine Programme; Chair of The Board of the National Institute of Academic Anaesthesia; A Director of Xtreme-Everest; Co-Chairman of Evidence Based Peri-operative Medicine (EBPOM). Board member and Chair of the advisory board of the American Society of Enhanced Recovery (ASER).

He was National Clinical Lead at the UK Department of Health for the Enhanced Recovery Partnership in the English NHS from May 09 - March 2013.

Featured articles from multi-institutional research groups

Design and methodology of SNAP-1: a Sprint National Anaesthesia Project to measure patient reported outcome after anaesthesia by Moonesinghe SR, Walker EMK and Bell M. Perioperative Medicine 2015, 4:4

Perioperative fluid therapy: a statement from the international Fluid Optimization Group by Navarro LHC, Bloomstone JA, Auler JOC, Cannesson M, Rocca GD, Gan TJ, Kinsky M, Magder S et al. Perioperative Medicine 2015, 4:3