AcumenTM hypotension prediction index guidance for prevention and treatment of hypotension in noncardiac surgery: a prospective, single-arm, multicenter trial

Table 4 Model effect estimates, sensitivity analyses

Model^a	Effect estimate^b (95% CI)	P value
Duration of hypotension (MAP < 65)
Crude	− 0.31 (− 0.39 to − 0.22)	< 0.001
Propensity adjusted	− 0.33 (− 0.41 to − 0.24)	< 0.001
Inverse probability of treatment weighting	− 0.35 (− 0.43 to − 0.27)	< 0.001
Multiple imputation propensity adjustment	− 0.33 (− 0.41 to − 0.25)	< 0.001
Post hoc sensitivity–adjusted for sex	− 0.35 (− 0.32 to − 0.27)	< 0.001
Acute kidney injury
Crude	0.93 (0.67 to 1.27)	0.674
Propensity adjusted	0.83 (0.60 to 1.14)	0.270
Inverse probability of treatment weighting	0.91 (0.63 to 1.33)	0.637
Multiple imputation propensity adjustment	0.88 (0.65 to 1.20)	0.432
Post hoc sensitivity–adjusted for sex	0.90 (0.61 to 1.31)	0.571

CI confidence interval: MAP mean arterial blood pressure
^aAll models are adjusting for time in which blood pressure is measured (i.e., time at risk)
^bEffect estimates for hypotension are reported as exponentiated beta coefficients (i.e., ratio of expected geometric means), whereas effect estimates for acute kidney injury are reported as odds ratios

ISSN: 2047-0525