AcumenTM hypotension prediction index guidance for prevention and treatment of hypotension in noncardiac surgery: a prospective, single-arm, multicenter trial

Table 3 Comparison of intraoperative hypotension and acute kidney injury in the single-arm trial versus contemporaneous comparison group

	Contemporaneous comparison N = 15,796	Trial N = 457	Crude model^b		Inverse probability of treatment weighing propensity model
	Contemporaneous comparison N = 15,796	Trial N = 457	Effect Estimate^c (95% CI)	P-Value	Effect estimate^c (95% CI)	P value
Duration of Hypotension (MAP < 65)^a	15 [5, 39]	9 [3, 20]	− 0.31 (− 0.39 to − 0.22)	< 0.001	− 0.35 (− 0.43 to − 0.27)	< 0.001
Acute kidney injury	1898/12,421 (15.3%)	45/325 (13.8%)	0.93 (0.67 to 1.27)	0.674	0.91 (0.63 to 1.33)	0.637

CI confidence interval: MAP mean arterial blood pressure)
Data is presented as median [quartile 1, quartile 3] in minutes, or n (%) depending on descriptive statistics
^aData is only available for 15,749 observations
^bAll models are adjusting for time in which blood pressure is measured (i.e., time at risk)
^cEffect estimates for hypotension are reported as exponentiated beta coefficients, whereas effect estimates for acute kidney injury are reported as odds ratios

ISSN: 2047-0525