| Effectiveness including subjects with no episodes of MAP < 65 mmHg | Effectiveness among subjects with at least 1 min of MAP < 65 mmHg | ||
---|---|---|---|---|
 | Trial participants (n = 406) | Historical comparison cohort (n = 22,109) | Trial participants (n = 293) | Historical comparison cohort (n = 19,446) |
 | Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) |
Trial primary outcome | Â | Â | Â | Â |
Duration of intraoperative hypotension (minutes of MAP < 65 mmHg) | 9 (13)* | 25 (41) | 12 (14)* | 28 (43) |
Trial secondary outcome | Â | Â | Â | Â |
Area under MAP of 65 mmHg (mmH × minute) | 47 (85) | na | 65 (94) | na |