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Table 4 Intraoperative characteristics of the whole cohort and unadjusted odds ratios for initial poor graft function

From: Sevoflurane preconditioning in living liver donation is associated with better initial graft function after pediatric transplantation: a retrospective study

 

Whole cohort (n = 183)

No IPGF (n = 141)

IPGF (n = 42)

OR for IPGF (95%CI)

P value

Donor

 Hypnotic

  Sevoflurane

69 (37.7)

58 (41.1)

11 (26.2)

1.00 (reference)

 

  Propofol

85 (46.4)

66 (46.8)

19 (45.2)

1.69 (0.67–3.45)

.32

  Propofol + sevoflurane

29 (15.8)

17 (12.1)

12 (28.6)

3.72 (1.40–9.92)

.0008

 NSAIDs

143 (78.1)

111 (78.7)

32 (76.2)

0.86 (0.38–1.96)

.73

 Sufentanil

71 (38.8)

60 (42.6)

11 (26.2)

0.48 (0.22–1.03)

.06

 Clonidine

136 (74.3)

104 (79.8)

32 (76.2)

1.14 (0.51–2.54)

.75

 Ketamine

178 (97.3)

136 (96.5)

42 (100.0)

NAa

NAa

 Epidural

152 (83.1)

117 (83.0)

35 (83.3)

1.03 (0.41–2.58)

.96

 Noradrenalin use

50 (27.3)

37 (26.2)

13 (31.0)

1.26 (0.59–2.68)

.55

Receiver

 Procedure duration (min)

648 [589–699]

642 [583–696]

675 [638–725]

1.45 (1.09–1.91)

.009

 Ischemia duration (min)

143 [123–170]

142 [120–168]

147 [125–180]

1.01 (0.99–1.02)

.16

 Vasopressor use

158 (86.3)

120 (85.1)

38 (90.5)

1.66 (0.54–5.15)

.38

 Lactate peak (mmol/L)

5.1 [4–6.8]

5.3 [4.1–7.0]

5.1 [3.9–6.2]

0.98 (0.85–1.14)

.84

 Reperfusion syndrome

31 (16.9)

24 (17.0)

7 (16.7)

0.98 (0.39–2.45)

.96

 Graft weight/body weight (%)

2.7 [1.9–3.5]

2.8 [2.0–3.7]

2.1 [1.7–3.2]

0.71 (0.51–0.99)

.03

  1. Data are presented as median [IQR] or numbers (%). Logistic regression was used to estimate odds ratios with 95% confidence intervals for IPGF
  2. Abbreviation: NSAIDs Non-steroidal anti-inflammatory drugs
  3. aUnstable estimate as there were no pairs where the donor received ketamine and the recipient developed IPGF