Preoperative endothelial dysfunction for the prediction of acute kidney injury after cardiac surgery using cardiopulmonary bypass: a pilot study based on a second analysis of the MONS study

Table 2 Microcirculatory assessment results according to acute kidney injury occurrence

Test	Variable	AKI	No AKI	p
Iontophoresis ACh (n = 60)	Peak amplitude, LSPU	35 [20–49]	23 [9–44]	0.04
	Time-to-peak, s	117 [90–143]	102 [73–138]	0.10
	AUC at 3 min, PU/s	9114 [7373–11,141]	5942 [5200–11,197]	0.40
Iontophoresis SNP (n = 60)	Peak amplitude, LSPU	34 [22–49]	36 [20–50]	0.95
	Time-to-peak, s	213 [162–251]	219 [172–230]	0.95
	AUC at 3 min, PU/s	8097 [6735–9896]	7711 [6674–10,140]	0.61
LTH (n = 59)	Peak amplitude, LSPU	60 [48–75]	55 [42–69]	0.38
	Time-to-peak, s	216 [186–224]	225 [205–242]	0.04
	Plateau amplitude, PU/s	73 [58–93]	69 [49–90]	0.99

Data presented have been filtered by subtracting movement artifacts and are expressed as median [interquartile range]. The p value was obtained for patients with and without AKI using the Mann–Whitney U test
LSPU laser speckle perfusion unit, ACh acetylcholine, SNP sulfate nitroprusside, LTH local thermal hyperemia

ISSN: 2047-0525