Postoperative and postdischarge nausea and vomiting following ambulatory eye, head, and neck surgeries: a retrospective cohort study comparing incidence and associated factors

Table 3 Binary logistic regression for PDNV vs no PDNV

Comparison	Outcome: PDNV vs. no PDNV
Comparison	AOR (95% CI)	p value
Patient characteristics
Age (per 1 year increase)	0.99 (0.98, 1)	0.002
Male sex	0.63 (0.51, 0.76)	< 0.001
ASA
2 vs 1	0.99 (0.77, 1.27)	0.945
3 vs 1	1.02 (0.69, 1.49)	0.935
3 vs 2	1.02 (0.75, 1.4)	0.876
Body mass index (per 1 kg/m² increase)	0.98 (0.96, 0.99)	0.012
Current smoker	0.74 (0.51, 1.08)	0.115
Otolaryngology service ( vs. ophthalmology)	0.87 (0.66, 1.14)	0.319
Pre/intraoperative anesthesia characteristics
Total anesthesia time (per 1 min increase)	1 (1, 1)	0.276
Inhalational time (per 1 min increase)	1 (1, 1)	0.77
Nitrous time (per 1 min increase)	1 (1, 1)	0.839
Propofol-only TIVA	0.62 (0.41, 0.94)	0.025
Pre/intraoperative/PACU anesthesia characteristics
PACU phase 1 time (per 1 min increase)	1 (1, 1)	0.938
PACU phase 2 time (per 1 min increase)	1 (1, 1)	< 0.001
Number of antiemetics used
1 vs. 0	0.84 (0.35, 1.98)	0.683
2 vs. 0	0.88 (0.38, 2.01)	0.757
3 vs. 0	0.67 (0.28, 1.59)	0.363
4 vs. 0	0.2 (0.05, 0.84)	0.028
Opioid use (per 1 MME increase)	1.01 (1, 1.01)	< 0.001
PONV	2.79 (2.24, 3.46)	< 0.001

Variables related to antiemetic and opioid drug use include all drugs administered intraoperatively and in the PACU. The antiemetics used variable includes ondanestron, scopolamine, dexamethasone, and promethazine Abbreviations: N/V nausea/vomiting, PONV postoperative nausea/vomiting, PDNV postdischarge nausea/vomiting, AOR adjusted odds ratio, ASA American Society of Anesthesiologists, TIVA total intravenous anesthesia, MME morphine milligram equivalents

ISSN: 2047-0525