Postoperative and postdischarge nausea and vomiting following ambulatory eye, head, and neck surgeries: a retrospective cohort study comparing incidence and associated factors

Table 2 Binary logistic regression for PONV vs no PONV

Comparison	Outcome: PONV vs. no PONV
Comparison	AOR (95% CI)	p value
Patient characteristics
Age (per 1 year increase)	0.99 (0.99, 0.99)	< 0.001
Male sex	0.44 (0.39, 0.5)	< 0.001
ASA
2 vs 1	0.81 (0.69, 0.94)	0.007
3 vs 1	0.77 (0.61, 0.97)	0.029
3 vs 2	0.95 (0.79, 1.15)	0.606
Body mass index (per 1 kg/m² increase)	1.01 (1, 1.02)	0.155
Current smoker	0.7 (0.56, 0.87)	0.002
Otolaryngology service (vs. ophthalmology)	1.24 (1.04, 1.47)	0.015
Pre/intraoperative anesthesia characteristics
Total anesthesia time (per 1 min increase)	1 (1, 1)	0.816
Inhalational time (per 1 min increase)	1.01 (1.01, 1.01)	< 0.001
Nitrous time (per 1 min increase)	1.01 (1, 1.01)	< 0.001
Propofol-only TIVA	0.69 (0.53, 0.91)	0.008
Number of prophylactic antiemetics
1 vs. 0	1.09 (0.69, 1.73)	0.715
2 vs. 0	0.86 (0.55, 1.34)	0.503
3 vs. 0	1.17 (0.73, 1.86)	0.51
Opioid use (per 1 MME increase)	1 (1, 1.01)	0.042

Variables related to antiemetic and opioid drug use include all drugs administered pre-PACU. The number of prophylactic antiemetics used a variable (ondansetron, scopolamine, and dexamethasone) does not include promethazine due to the limited number of patients who received it pre-PACU (n = 4)
Abbreviations: N/V nausea/vomiting, PONV postoperative nausea/vomiting, AOR adjusted odds ratio, ASA American Society of Anesthesiologists, TIVA total intravenous anesthesia, MME morphine milligram equivalents

ISSN: 2047-0525