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Table 3 Changes in outcome measure associated with prehabilitationa

From: Multidisciplinary prehabilitation to improve frailty and functional capacity in high-risk elective surgical patients: a retrospective pilot study

 

Baseline

(95% CI)

End of prehabilitation

(95% CI)

Difference

(95% CI)

p-value

Exercise capacity

 6MWT (m) (n = 52)

393.6 (362.8 to 424.4)

429.3 (399.4 to 459.2)

35.7 (-4.6 to 75.9)

0.082

 VO2peak (ml kg−1 min−1) (n = 52)

10.9 (10.0 to 11.8)

11.1 (10.2 to 12.0)

0.2 (-0.8 to 1.2)

0.686

Muscle strength

 Right hand grip strength (kg) (n = 52)

23.7 (21.3 to 26.2)

25.6 (22.9 to 28.3)

1.9 (-0.9 to 4.6)

0.180

 Left hand grip strength (kg) (n = 52)

22.9 (20.4 to 25.4)

25.2 (22.5 to 27.9)

2.3 (-0.4 to 5.0)

0.094

 30-s chair stand (times) (n = 52)

12.0 (10.8 to 13.3)

13.2 (11.7 to 14.6)

1.1 (-0.8 to 3.0)

0.245

Functional mobility

 Timed Up and Go (s) (n = 52)

10.8 (9.5 to 12.0)

8.7 (7.5 to 9.9)

-2.1 (-3.7 to-0.4)

0.015

 mFAC (n = 52)

6.6 (6.4 to 6.8)

6.9 (6.6 to 7.1)

0.3 (-0.1 to 0.7)

0.195

 mRMI (n = 52)

38.6 (38.1 to 39.2)

39.4 (39.0 to 39.9)

0.8 (0.1 to 1.5)

0.022

 MFS (n = 51)

15.8 (12.7 to 18.9)

14.6 (11.1 to 18.2)

-1.1 (-3.2 to 0.9)

0.264

 mBI (n = 51)

98.7 (97.5 to 99.8)

99.6 (98.5 to 100.8)

1.0 (-0.9 to 2.8)

0.313

 LawADL (n = 51)

6.0 (5.6 to 6.4)

6.2 (5.8 to 6.5)

0.2 (0.0 to 0.4)

0.080

Cognitive function

 MOCA (n = 52)

21.8 (20.7 to 22.9)

22.5 (21.2 to 23.8)

0.7 (-0.7 to 2.2)

0.303

Emotional resilience

 DASS_Depression (n = 50)

6.4 (3.6 to 9.1)

4.8 (2.3 to 7.4)

-1.5 (-5.5 to 2.5)

0.461

 DASS_Anxiety (n = 50)

6.4 (4.2 to 8.5)

5.7 (3.2 to 8.2)

-0.7 (-4.3 to 2.9)

0.710

 DASS_Stress (n = 50)

6.4 (3.3 to 9.5)

7.7 (4.9 to 10.6)

1.3 (-3.6 to 6.3)

0.598

Nutritional status outcomes

 Weight (kg)

59.8 (56.1 to 63.5)

59.4 (55.8 to 63.0)

-0.4 (-0.9 to 0.2)

0.193

 BMI (kg.m−2) (n = 31)

23.1 (21.9 to 24.3)

22.7 (21.6 to 23.9)

-0.4 (-0.6 t-0.1)

0.018

 Skeletal muscle mass (kg) (n = 28)

18.5 (17.0 to 20.0)

18.6 (16.4 to 20.9)

0.1 (-2.1 to 2.3)

0.899

 Fat percentage of weight (%) (n = 28)

24.5 (20.7 to 28.3)

24.0 (20.2 to 27.8)

-0.5 (-1.9 to 0.8)

0.450

 Daily energy intake (kcal.body weight−1) (n = 31)

26.9 (25.2 to 28.5)

28.3 (26.5 to 30.1)

1.4 (0.1 to 2.8)

0.038

 Daily protein intake (g.body weight−1) (n = 31)

1.1 (1.0 to 1.2)

1.2 (1.1 to 1.2)

0.1 (0 to 0.1)

0.006

  1. Abbreviations: mFAC Modified Functional Ambulatory Category, mRMI Modified Rivermead Mobility Index, MFS Morse Fall Scale, MBI Modified Barthel Index for activity daily living, LawADL Lawton Instrumental Activities of Daily Living, MOCA Montreal Cognitive Assessment
  2. aAdjusted results using generalized estimating equations