Perioperative myocardial injury is associated with increased postoperative non-cardiac complications in patients undergoing vascular surgery: a post hoc analysis of a randomised clinical pilot trial

Table 4 Association between clinical characteristics and non-cardiac complication

Variable	Unadjusted OR	P value	Adjusted OR	P value
Pre-operative hs cTnT	1.08 (0.81–1.45)	0.60	1.06 (0.77–1.44)	0.73
Pre-operative NT-proBNP	1.36 (0.93–1.97)	0.11	1.36 (0.90–2.04)	0.15
PMI	2.85 (1.44–5.65)	< 0.01	2.71 (1.33–5.52)	0.01
ASA classification	1.62 (0.81–3.26)	0.17	1.83 (0.88–3.81)	0.10
BMI > 30	0.77 (0.37–1.60)	0.48	0.81 (0.37–1.78)	0.60
Intra-operative bleeding > 500 ml	1.77 (0.89–3.51)	0.10	1.26 (0.61–2.61)	0.53
Duration of surgery > 120 min	3.69 (1.45–9.40)	0.01	3.33 (1.17–9.47)	0.02

PMI: generalised estimating equation (GEE) regression models were used to adjust for repeated measurement of troponin, intervention (hyperoxia vs. normoxia), endovascular surgery and duration of surgery. Other variables: logistic regression was used for unadjusted analysis and multiple regression analysis was used to adjust for intervention in the HYPEROXIA-trial, endovascular surgery, and duration of operation Abbreviations: PMI = peri-operative myocardial injury, ASA = American Society of Anaesthesiologists

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