Table 1 Data collection throughout the trial

Baseline data

 1. General information including age, gender, height, weight, BMI, ASA level

 2. Hospitalization information including admission date and type and preoperative diagnosis

 3. Medical history: Smoking and alcohol history, history of cardiovascular diseases and related surgery, cerebral and perivascular diseases, diabetes, and preoperative medication

 4. Auxiliary examination including ECG, echocardiography, blood routine examination, biochemistry and clotting examination, serum hs-cTnT level

Intraoperative data

 1. Surgery information: Surgery date, duration, and type

 2. Anesthesia information: Total anesthetics amount, dose of vasoactive drugs, and capacity parameters (blood loss, liquid infusion, urine volume)

 3. Adverse events including hypotension and bradycardia

Postoperative data

 1. Serum hs-cTnT level and ECG with the occurrence of MINS within 72 h

 2. Myocardial ischemic symptoms

 1. MACE including myocardial infarction, heart block, cardiac arrest, stroke, and coma during hospital stay

 2. Adverse events including hypotension and bradycardia and other complications including sepsis, pneumonia, liver dysfunction, and renal dysfunction

 1. Length of ICU and postoperative hospital stay

 2. All-cause mortality within 30 days