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Table 6 IPACK block with PNB

From: Periarticular injection, iPACK block, and peripheral nerve block in pain management after total knee arthroplasty: a structured narrative review

Year

Author

Type of study

Sample size

Method

Results

2018

Sankineani et al. (2018a; 2018b)

Prospective study

120

iPACK with ACB vs ACB alone

iPACK with ACB was more effective in reducing pain after TKA (p < 0.005)

2021

Wang et al. (2021a; 2021b)

A prospective, randomized, double-blind study

149

iPACK with ACB + sham obturator nerve block (ONB) + sham lateral femoral cutaneous nerve block (LFCNB) vs ACB + iPACK + ONB + LFCNB vs ACB + iPACK + ONB + sham LFCNB

iPACK + ACB + ONB + LFCNB was more effective in reducing morphine consumption after TKA (p < 0.01)

2020

Ochroch et al. (2020)

A prospective, randomized, double-blind study

119

iPACK + ACB vs sham block + ACB

 

2022

Wang et al. (2022)

A prospective, randomized, double-blind study

70

Continuous ACB + iPACK vs CACB + sham block

ACB + iPACK was more effective in reducing pain after TKA (p < 0.05)

2022

Mou et al. (Mou et al. 2022)

A prospective, randomized, double-blind study

120

ACB + iPACK vs ACB vs iPACK

ACB + iPACK was more effective in reducing pain after TKA (p < 0.001)

2022

Et et al. (Et et al. 2022)

Prospective, randomized, double-blind study

105

ACB vs iPACK + ACB vs LIA + ACB

ACB + iPACK was more effective in reducing pain after TKA (p < 0.05)

2022

Tak et al. (2020)

A prospective, randomized, double-blind study

171

ACB vs continuous ACB vs ACB + iPACK

CACB was more effective in reducing pain after TKA (p < 0.05)

2020

Li et al. (2020)

A prospective, randomized, double-blind study

200

ACB + iPACK + lateral femoral cutaneous nerve block vs ACB + iPACK vs ACB + lateral cutaneous nerve block vs ACB alone

ACB + iPACK + lateral femoral cutaneous nerve block was more effective in reducing pain after TKA (p < 0.05)

2021

Kampitak et al. (Kampitak et al. 2021)

A prospective, randomized, double-blind study

72

Selective sensory nerve blockade (ACB + anterior femoral cutaneous nerve block + iPACK) vs LIA

SSNB did not provide superior postoperative analgesia

2022

Abdullah et al. (Abdullah et al. 2022)

A prospective, randomized controlled trial

80

iPACK with ACB vs ACB alone

ACB + iPACK was more effective in reducing pain after TKA (p < 0.01)