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Table 3 PAI with PNB

From: Periarticular injection, iPACK block, and peripheral nerve block in pain management after total knee arthroplasty: a structured narrative review

Year

Author

Type of study

Sample size

Method

Results

2019

Aso et al. (2019)

A prospective single-center double-blind, randomized controlled trial

40

PAI with a femoral nerve block (FNB) vs FNB alone

PAI with FNB was more effective in reducing pain after TKA (p < 0.05)

2018

Fenton et al. (2018)

A prospective single-center double-blind, randomized controlled trial

80

PAI vs PAI with FNB catheter

PAI with FNB was more effective in reducing pain after TKA (p < 0.005)

2020

Kampitak et al. (2020)

A prospective single-center double-blind, randomized controlled trial

90

PAI with continuous adductor canal block with (1) obturator nerve block vs (2) tibial nerve block vs (3) obturator and tibial nerve block

PAI with triple nerve block was more effective in reducing pain after TKA (p < 0.05)

2018

Biswas et al. (2018)

A prospective single-center double-blind, randomized controlled trial

201

PAI with sham adductor canal block (ACB) vs PAI with adductor canal block vs PAI with intrathecal morphine

PAI with ACB was more effective in reducing pain after TKA (p = 0.007)

2022

Luo et al. (2022)

A prospective single-center, double-blind, randomized controlled trial

86

PAI vs PAI with ACB

PAI with ACB was more effective in reducing pain after TKA (p < 0.05)

2018

Tziona et al. (2018)

A prospective single-center, double-blind, randomized controlled trial

40

PAI vs PAI with ACB

PAI with ACB was more effective in reducing morphine consumption (p < 0.05)

2019

Lan et al. (2019)

Double-blind, randomized, placebo-controlled trial

46

PAI vs PAI with CACB

PAI with CACB was more effective in reducing pain after TKA (p < 0.001)

2017

Gudmundsdottir et al. (2017)

Randomized, double-blind, placebo-controlled trial

69

PAI vs PAI with CACB

CACB added to PAI showed no benefit