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Table 1 Baseline demographics and clinical characteristics of the patients who underwent craniotomy for primary malignant brain tumor

From: Significant perioperative parameters affecting postoperative complications within 30 days following craniotomy for primary malignant brain tumors

 

Total

Without complication

With complication

 

Variable*

n = 95 (%)

n = 54 (%)

n = 41 (%)

p-value

Age, years (IQR)

57 (48 ~ 67)

57 (49 ~ 67)

57 (46 ~ 66)

0.974

Age ≥ 60 years

41 (43)

24 (44)

17 (42)

0.771

Male

52 (55)

26 (48)

26 (63)

0.139

mFI-5 score

   

0.366

  < 2

60 (63)

32 (34)

28 (29)

 

  ≥ 2

35 (37)

22 (23)

13 (14)

 

Preoperative GCS (IQR)

15 (15 ~ 15)

15 (15 ~ 15)

15 (13 ~ 15)

-

Preoperative seizure

6 (6)

4 (7)

2 (5)

0.616

ASA score > 2

53 (56)

24 (44)

29 (71)

0.011

Preoperative laboratory data (IQR)

 WBC (K/µL)

9.0 (7.0 ~ 12.0)

8.5 (7.0 ~ 10.0)

9.0 (7.5 ~ 15.5)

0.059

 Hct (%)

41.0 (37.0 ~ 44.0)

41.0 (37.0 ~ 44.0)

41.0 (36.5 ~ 44.0)

0.884

 Hb (g/dL)

14.0 (12.0 ~ 15.0)

14.0 (12.0 ~ 15.0)

14.0 (12.0 ~ 15.0)

0.940

 Platelet (K/µL)

218 (186 ~ 281)

231 (190 ~ 286)

209 (183 ~ 275)

0.249

 Cr (mg/dL)

1.0 (1.0 ~ 1.0)

1.0 (1.0 ~ 1.0)

1.0 (1.0 ~ 1.0)

0.808

 BUN (mg/dL)

15 (12 ~ 19)

14 (12 ~ 18)

15 (12 ~ 22)

0.190

 eGFR (ml/min) (SD)

84.9 ± 23.3

86.7 ± 21.0

82.7 ± 26.1

0.409

 Na (mmol/L)

141 (138 ~ 142)

141 (138 ~ 142)

140 (138 ~ 142)

0.533

 K (mmol/L)

4.0 (4.0 ~ 4.0)

4.0 (4.0 ~ 4.0)

4.0 (4.0 ~ 4.0)

0.140

 GPT (U/L)

19 (15 ~ 33)

19 (14 ~ 31)

21 (16 ~ 40)

0.614

Pathological type

   

0.108

 Glioblastomas

70 (73.7)

41 (43.2)

29 (30.5)

 

 Anaplastic astrocytomas

10 (10.5)

3 (3.2)

7 (7.4)

 

 Anaplastic oligodendrogliomas

8 (8.4)

7 (7.4)

1 (1.1)

 

 Others

7 (7.4)

4 (4.2)

3 (3.2)

 

WHO grade

   

0.972

 3

23 (24)

13 (14)

10 (11)

 

 4

72 (76)

41 (43)

31 (33)

 

Duration of anesthesia (h) (IQR)

11.0 (9.0 ~ 13.0)

10.0 (8.0 ~ 13.0)

12.0 (9.5 ~ 14.5)

0.221

Tumor volume (cm3) (SD)

6.7 ± 1.7

6.6 ± 1.6

6.7 ± 1.7

0.642

  1. *Continuous data were tested for normality using the Kolmogorov–Smirnov test. Parametric continuous variables were presented as mean and standard deviation, and nonparametric data were presented as median and interquartile range. Abbreviations: SD Standard deviation, IQR Interquartile range, mFI-5 Modified 5-item frailty index, WHO World Health Organization, GCS Glasgow coma scale, ASA American Society of Anesthesiologists, WBC White blood cells count, Hct Hematocrit, Hb Hemoglobin, Cr Creatinine, BUN Blood urea nitrogen, eGFR Estimated glomerular filtration rate, Na Sodium, K Potassium, GPT Alanine aminotransferase, SBP Systolic blood pressure, DBP Diastolic blood pressure