Table 2 Coagulation assay values

PT (seconds)-mean (SD)

 Baseline^a

11.1 (0.9)

11.3 (0.7)

11.3 (0.7)

–

–

–

–

–

–

–

 Final

11.2 (0.8)

11.1 (0.8)

11.1 (0.8)

–

–

–

–

–

–

–

 Change

0.1 (0.5)

− 0.2 (0.4)

− 0.2 (0.4)

0.34

− 0.2 (− 0.6, 0.2)

0.27

− 0.3 (− 0.7, 0.1)

0.17

0.1 (− 0.3, 0.5)

0.77

INR-median (IQR)

 Baseline

1 (0.9, 1.1)

1 (1, 1.1)

1 (1, 1.1)

–

–

–

–

–

–

–

 Final

1 (1, 1.1)

1 (1, 1.1)

1 (1, 1.1)

–

–

–

–

–

–

–

 Change

0 (0, 0.1)

0 (− 0.1, 0)

0 (0, 0)

0.07

− 0.06 (− 0.1, − 0.01)

0.02

− 0.03 (− 0.07, 0.03)

0.31

− 0.03 (− 0.08, 0.02)

0.18

aPTT (seconds)-mean (SD)

 Baseline

33.6 (2.2)

33.7 (3)

34 (2.4)

–

–

–

–

–

–

–

 Final

33.4 (2.3)

33.2 (2.2)

33.4 (2.6)

–

–

–

–

–

–

–

 Change

− 0.2 (1)

− 0.5 (1.8)

 − 0.6 (1.6)

0.8

− 0.3 (− 1.7, 1.1)

0.8

− 0.5 (− 1.9, 0.9)

0.49

0.2 (− 1.2, 1.5)

0.8

TT (seconds)-mean (SD)

 Baseline

20.9 (1.5)

22.1 (1.6)

21.1 (1.5)

–

–

–

–

–

–

–

 Final

22.3 (1.4)

22 (1.1)

21.9 (1.2)

–

–

–

–

–

–

–

 Change

1.4 (1.4)

− 0.1 (1.8)

0.8 (1.6)

0.08

− 1.5 (− 2.9, − 0.2)

0.03

− 0.6 (− 1.9, 0.7)

0.35

− 0.9 (− 2.2, 0.4)

0.16

RT (seconds)-mean (SD)

 Baseline

15.1 (0.8)

15.3 (0.9)

15.1 (1.2)

–

–

–

–

–

–

–

 Final

14.9 (1)

15.2 (0.9)

15.1 (0.7)

–

–

–

–

–

–

–

 Change

-0.1 (0.9)

0 (1.1)

0.1 (0.9)

0.8

0.1 (− 0.6, 0.9)

0.7

0.2 (− 0.5, 0.9)

0.56

 − 0.1 (− 0.8, 0.6)

0.79

FG (mg/dL)-mean (SD)

 Baseline

418.3 (69.8)

379.8 (53.2)

411 (72.3)

–

–

–

–

–

–

–

 Final

400.1 (47.3)

393.2 (54)

396.4 (70.2)

–

–

–

–

–

–

–

 Change

− 18.3 (63.7)

13.4 (43.4)

− 14.6 (42.6)

0.2

31.7 (− 8.7, 72.1)

0.1

3.7 (− 36.7, 44.1)

0.85

28.0 (− 12.4, 68.4)

0.16