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Table 2 Details of study medications

From: Effects of opioid-free total intravenous anesthesia on postoperative nausea and vomiting after treatments of lower extremity wounds: protocol for a randomized double-blind crossover trial

 

OFA

OBA

Anesthesia induction

Esketamine 0.2–0.4 mg/kg

Sufentanil 0.2–0.4 μg/kg

 

Lidocaine 1 mg/kg

Normal saline

 

Propofol 1.5–2.0 mg/kg

Propofol 1.5–2.0 mg/kg

Anesthesia maintenance

Dexmedetomidine 0.3–1.0 μg/kg/h

Normal saline infusion

 

Esketamine 0.1 mg/kg boluses

Sufentanil 0.1 μg/kg boluses

 

Propofol 2–10 mg/kg/h

Propofol 2–10 mg/kg/h

  1. OFA opioid-free anesthesia, OBA opioid-based anesthesia