Table 2 Organ system toxicity and the associated chemotherapeutic agent
From: Review of cancer therapies for the perioperative physician
Organ system toxicity | Chemotherapeutic agent |
|---|---|
Pulmonary | Antitumor antibiotics, alkylating agents, antimetabolites, plant alkaloids |
Cardiovascular | Antitumor antibiotics (anthracyclines and mitomycin), plant alkaloids, alkylating agents (cyclophosphamide, ifosfamide, cisplatin, busulfan, carmustine, chlormethine), antimetabolite (5‐FU) |
Hepatobiliary | Alkylating (nitrosoureas, platinums, nitrogen mustards) antimetabolites (5-FU), antitumor antibiotics, plant alkaloids |
Renal | Antitumor antibiotics, antimetabolites, alkylating agents |