From: Sex differences in myocardial injury after non-cardiac surgery and postoperative mortality
Entire population | ||||
---|---|---|---|---|
Male (N = 18,546) | Female (N = 14,765) | P value | SMD | |
Age | 62.01 (13.4) | 62.48 (14.0) | 0.002 | 3.5 |
Diabetes | 10,102 (54.5) | 6819 (46.2) | < 0.001 | 16.6 |
Hypertension | 10,518 (56.7) | 8187 (55.4) | 0.02 | 2.5 |
Current smoking | 3015 (16.3) | 272 (1.8) | < 0.001 | 51.9 |
Current alcohol | 5398 (29.1) | 1204 (8.2) | < 0.001 | 55.9 |
Chronic kidney disease | 1195 (6.4) | 645 (4.4) | < 0.001 | 9.2 |
History of ischemic heart disease | 3356 (18.1) | 1593 (10.8) | < 0.001 | 20.9 |
History of heart failure | 407 (2.2) | 553 (3.7) | < 0.001 | 9.1 |
History of stroke | 1365 (7.4) | 841 (5.7) | < 0.001 | 6.7 |
History of arrhythmia | 1382 (7.5) | 820 (5.6) | < 0.001 | 7.7 |
History of heart valve disease | 188 (1.0) | 240 (1.6) | < 0.001 | 5.4 |
Active cancer | 9274 (50.0) | 5123 (34.7) | < 0.001 | 31.4 |
Preoperative care | ||||
Intensive care unit | 768 (4.1) | 475 (3.2) | < 0.001 | 4.9 |
ECMO | 1 (0.0) | 0 (0.0) | > 0.99 | 1 |
Continuous renal replacement therapy | 50 (0.3) | 30 (0.2) | 0.26 | 1.4 |
Ventilator | 134 (0.7) | 86 (0.6) | 0.13 | 1.7 |
Operative variables | ||||
ESC/ESA surgical high risk | 4737 (25.5) | 1978 (13.4) | < 0.001 | 31 |
Emergency operation | 2668 (14.4) | 1963 (13.3) | 0.004 | 3.2 |
General anesthesia | 17,158 (92.5) | 11,997 (81.3) | < 0.001 | 33.8 |
Operation duration, hours | 3.38 (2.27) | 2.80 (2.05) | < 0.001 | 26.8 |
Continuous infusion of inotropics | 5447 (29.4) | 4217 (28.6) | 0.11 | 1.8 |
RBC transfusion | 1559 (8.4) | 895 (6.1) | < 0.001 | 9.1 |