Table 3 Perioperative mean change in serum laboratory parameters of patients who underwent craniotomy for primary malignant brain tumor

Variable (mean ± SD)

n = 95 (%)

n = 54 (%)

n = 41 (%)

p-value

WBC (K/µL)

4.7 ± 5.6

5.8 ± 5.1

3.3 ± 6.1

0.031

Hct (%)

 − 4.8 ± 4.1

 − 5.4 ± 3.5

 − 4.1 ± 4.6

0.138

Hb (g/dL)

 − 1.6 ± 1.4

 − 1.7 ± 1.2

 − 1.5 ± 1.7

0.390

Platelet (K/µL)

 − 33.7 ± 42.9

 − 34.2 ± 33.4

 − 33.1 ± 53.3

0.904

Cr (mg/dL)

 − 0.1 ± 0.2

 − 0.1 ± 0.3

0.0 ± 0.2

0.620

BUN (mg/dL)

 − 0.3 ± 5.8

 − 1.0 ± 5.5

0.6 ± 6.2

0.184

eGFR (ml/min)

13.3 ± 27.9

16.8 ± 30.9

8.8 ± 23.1

0.167

Na (mmol/L)

1.2 ± 4.7

0.7 ± 3.9

1.8 ± 5.6

0.254

K (mmol/L)

 − 0.2 ± 0.7

 − 0.2 ± 0.6

 − 0.1 ± 0.8

0.885

GPT (U/L)

0.1 ± 30.1

2.4 ± 19.7

 − 3.0 ± 40.0

0.382

KeGFR (mL/min)

 − 0.4 ± 6.7

0.9 ± 6.3

 − 2.0 ± 7.1

0.041