Table 3 Multivariable association with absolute and relative MAP thresholds after tumor resection and postoperative AKI
Threshold | AKI (n = 48) | No AKI (n = 512) | Adjusted OR (95% CI)* | P values* |
|---|---|---|---|---|
Baseline MAP, mmHg | 94 ± 11 | 90 ± 11 | 1.02 (0.99, 1.05) | 0.19 |
Time under absolute MAP | ||||
MAP < 85 mmHg | ||||
0 min, n (%) | 1 (2.1) | 53 (10.4) | Ref | 0.050 |
1–19 min, n (%) | 3 (6.3) | 95 (18.6) | 2.07 (0.20, 21.51) | |
≥ 20 min, n (%) | 44 (91.7) | 364 (71.1) | 5.21 (0.68, 40.05) | |
MAP < 80 mmHg | ||||
0 min, n (%) | 1 (2.1) | 107 (20.9) | Ref | 0.004 |
1–19 min, n (%) | 11 (22.9) | 157 (30.7) | 8.88 (1.09, 72.42) | |
≥ 20 min, n (%) | 36 (75.0) | 248 (48.4) | 11.16 (1.46, 85.10) | |
MAP < 75 mmHg | ||||
0 min, n (%) | 4 (8.3) | 201 (39.3) | Ref | < 0.001 |
1–19 min, n (%) | 15 (31.3) | 192 (37.5) | 3.24 (1.02, 10.29) | |
≥ 20 min, n (%) | 29 (60.4) | 119 (23.2) | 7.94 (2.61, 24.18) | |
MAP < 70 mmHg | ||||
0 min, n (%) | 11 (22.9) | 340 (66.4) | Ref | < 0.001 |
1–19 min, n (%) | 22 (45.8) | 140 (27.3) | 4.87 (2.20, 10.80) | |
≥ 20 min, n (%) | 15 (31.3) | 32 (6.3) | 9.21 (3.37, 25.14) | |
MAP < 65 mmHg | ||||
0 min, n (%) | 20 (41.7) | 432 (84.4) | Ref | < 0.001 |
1–19 min, n (%) | 19 (39.6) | 73 (14.3) | 4.43 (2.09, 9.35) | |
≥ 20 min, n (%) | 9 (18.8) | 7 (1.4) | 6.04 (1.75, 20.89) | |
Time under relative MAP Thresholds | ||||
MAP decrease from baseline > 10% | ||||
0 min, n (%) | 3 (6.3) | 140 (27.3) | Ref | 0.005 |
1–19 min, n (%) | 4 (8.3) | 106 (20.7) | 2.09 (0.44, 9.92) | |
≥ 20 min, n (%) | 41 (85.4) | 266 (52.0) | 5.01 (1.47, 17.08) | |
MAP decrease from baseline > 15% | ||||
0 min, n (%) | 3 (6.3) | 201 (39.3) | Ref | < 0.001 |
1–19 min, n (%) | 11 (22.9) | 125 (24.4) | 5.97 (1.57, 22.71) | |
≥ 20 min, n (%) | 34 (70.8) | 186 (36.3) | 7.86 (2.29, 26.94) | |
MAP decrease from baseline > 20% | ||||
0 min, n (%) | 6 (12.5) | 262 (51.2) | Ref | < 0.001 |
1–19 min, n (%) | 12 (25.0) | 120 (23.4) | 3.22 (1.12, 9.25) | |
≥ 20 min, n (%) | 30 (62.5) | 130 (25.4) | 6.63 (2.56, 17.14) | |
MAP decrease from baseline > 25% | ||||
0 min, n (%) | 7 (14.6) | 339 (66.2) | Ref | < 0.001 |
1–19 min, n (%) | 23 (47.9) | 106 (20.7) | 8.77 (3.50, 21.98) | |
≥ 20 min, n (%) | 18 (37.5) | 67 (13.1) | 6.53 (2.42, 17.66) | |
MAP decrease from baseline > 30% | < 0.001 | |||
0 min, n (%) | 18 (37.5) | 406 (79.3) | Ref | |
1–19 min, n (%) | 16 (33.3) | 80 (15.6) | 3.63 (1.67, 7.88) | |
≥ 20 min, n (%) | 14 (29.2) | 25 (4.9) | 5.36 (2.09, 13.75) | |