| IV-morphine group (n = 15) | SL-sufentanil group (n = 15) | p |
---|---|---|---|
Total of IV morphine equivalents consumed (PACU and ward) | 13 [8.5–19] | 40 [9.5–70] | 0.03 |
 Morphine equivalents consumed in the PACU | 6 [0–8] | 2.5 [2.5–5] | 0.93 |
 Morphine equivalents consumed in the ward (mg) | 8 [3.8–13] | 37.5 [11.3–58.8] | 0.03 |
Opioid consumption in the PACU | |||
 IV morphine or SSTS titration | 12 (80%) | 15 (100%) | 0.22 |
 IV morphine titration | 12 (75%) | 4 (27%) | <0.01 |
 IV morphine dose (when received) (mg) | 6.5 [5.5–8.5] | 6 [3–7.5] | 0.47 |
 SSTS titration | - | 13 (100%) | - |
 Number of requested bolus | - | 1 [1–2] | - |
 Number of received bolus | - | 1 [1–2] | - |
 Sublingual sufentanil (μg) | - | 15 [15–30] | - |
Opioid consumption in the surgical ward | |||
 Total of requested bolus on PCA or SSTS | 3 [2–9] | 15 [4.5–25] | 0.11 |
 Total of received bolus on PCA or SSTS | 3 [2–10.5] | 15 [4.5–23] | 0.09 |
 Total of oxycodone tablets consumed | 1 [0.5–2] | 0 [0–0] | <0.01 |
 Total of IV morphine equivalents consumed (mg) | 8 [3.8–13] | 37.5 [11.3–58.8] | 0.03 |
 Total of IV morphine (mg) | 3 [2–10.5] | - | - |
 Total of sublingual sufentanil (μg) | - | 225 [67.5–345] | - |
 Total of oral oxycodone (mg) | 5 [2.5–10] | 0 [0–0] | <0.01 |
Postoperative pain at rest | |||
 NRS day 0 | 1.5 [1–2] | 2 [1–3] | 0.61 |
 NRS day 1 | 2 [1.6–3] | 1.6 [1–2.6] | 0.19 |
 NRS day 2 | 1 [0–2] | 1.6 [0.3–3.7] | 0.27 |
 NRS day 3 | 1.3 [0.5–2.2] | 1.5 [0.3–2] | 0.88 |
Postoperative pain on exertion | |||
 NRS day 0 | 3 [2–6] | 4 [1–6] | 0.44 |
 NRS day 1 | 4 [3.8–5.3] | 6 [4–7] | 0.12 |
 NRS day 2 | 4 [2–6] | 4 [3–6] | 0.91 |
 NRS day 3 | 4 [2–6] | 2 [1.3–4.8] | 0.19 |
Opioid-related side effects | |||
 Nausea and vomiting | 4 (27%) | 6 (40%) | 0.70 |
 Constipation | 2 (13%) | 2 (13%) | 1 |
Peripheral venous cannula withdrawn | |||
 Day 0 | 0 (0%) | 12 (80%) | <0.01 |
 Day 1 | 0 (0%) | 15 (100%) | <0.01 |
 Day 2 | 7 (47%) | 15 (100%) | <0.01 |
 Day 3 | 13 (87%) | 14 (93%) | 0.55 |
Flexion of the operated knee (degrees) | |||
 Day 0 | 80 [80–80] | 82 [78–86] | 0.59 |
 Day 1 | 80 [60–90] | 80 [60–90] | 0.80 |
 Day 2 | 90 [80–95] | 90 [80–90] | 0.65 |
 Day 3 | 90 [87–90] | 90 [86–90] | 1 |
Length of stay in postanesthesia care unit (min) | 137 [125–164] | 133 [115–145] | 0.48 |
Length of hospital stay (days) | 4 [4–6] | 5 [4.5–7] | 0.34 |