Variable | Total (n = 890) | Non-PHLF failure (n = 859) | PHLF failure (n = 31) | p value |
---|---|---|---|---|
AST (U/L), mean ± SD | ||||
 Day 0, n = 766 | 306 + 424 | 279 + 297 | 1063 + 1481 | 0.011 |
 Day 1, n = 796 | 373 + 609 | 326 + 435 | 1567 + 1907 | 0.001 |
 Day 2, n = 412 | 322 + 550 | 271 + 379 | 1075 + 1463 | 0.009 |
 Day 3, n = 732 | 135 + 210 | 121 + 170 | 473 + 535 | 0.001 |
POD1 AST(U/L), n (%) n = 796 | ||||
 AST ≤ 260 | 469(58.92) | 466(60.84) | 3(10.00) | 0.000 |
 AST > 260 | 327(41.08) | 300(39.16) | 27(90.00) |  |
ALT (U/L), mean ± SD | ||||
 Day 0, n = 749 | 252 + 359 | 234 + 308 | 748 + 906 | 0.007 |
 Day 1, n = 784 | 322 + 431 | 295 + 368 | 971 + 995 | 0.001 |
 Day 2, n = 401 | 342 + 467 | 307 + 395 | 823 + 926 | 0.008 |
 Day 3, n = 728 | 208 + 252 | 193 + 214 | 561 + 601 | 0.002 |
POD1 ALT (U/L), n(%) n = 784 | ||||
 ALT ≤ 270 | 501(63.90) | 494(65.60) | 7(22.58) | 0.000 |
 ALT > 270 | 283(36.10) | 259(34.40) | 24(77.42) |  |
TB (mg/dL), mean ± SD | ||||
 Day 0, n = 766 | 1.70 + 3.03 | 1.66 + 3.06 | 2.78 + 1.98 | 0.007 |
 Day 1, n = 797 | 1.92 + 3.57 | 1.84 + 3.58 | 3.83 + 2.56 | 0.000 |
 Day 2, n = 413 | 2.63 + 6.53 | 2.52 + 6.72 | 4.25 + 1.87 | 0.001 |
 Day 3, n = 748 | 1.98 + 6.49 | 1.85 + 6.57 | 5.07 + 2.56 | 0.000 |
INR, mean ± SD | ||||
 Day 0, n = 772 | 1.14 + 0.14 | 1.14 + 0.13 | 1.28 + 0.18 | 0.000 |
 Day 1, n = 768 | 1.20 + 0.13 | 1.19 + 0.12 | 1.41 + 0.16 | 0.000 |
 Day 2, n = 366 | 1.26 + 0.16 | 1.25 + 0.14 | 1.47 + 0.18 | 0.000 |
 Day 3, n = 424 | 1.19 + 0.16 | 1.18 + 0.14 | 1.46 + 0.24 | 0.000 |
Alb (g/L), mean ± SD | ||||
 Day 0, n = 853 | 28.51 + 4.98 | 28.58 + 4.95 | 26.64 + 5.50 | 0.033 |
 Day 1, n = 825 | 27.76 + 3.89 | 27.76 + 3.84 | 27.68 + 5.18 | 0.937 |
 Day 2, n = 741 | 27.52 + 4.18 | 27.47 + 4.15 | 28.51 + 4.88 | 0.179 |
 Day 3, n = 558 | 28.12 + 4.06 | 28.07 + 4.02 | 29.07 + 4.73 | 0.182 |
ALP (U/L), mean + SD | ||||
 Day 0, n = 766 | 86 + 52 | 85 + 50 | 128 + 92 | 0.022 |
 Day 1, n = 797 | 81 + 46 | 78 + 42 | 132 + 89 | 0.003 |
 Day 2, n = 412 | 82 + 51 | 78 + 38 | 137 + 126 | 0.023 |
 Day 3, n = 733 | 86 + 50 | 84 + 44 | 140 + 111 | 0.009 |