From: Perioperative statin medication impairs pulmonary outcome after abdomino-thoracic esophagectomy
Variable | All patients | Propensity score-matched patients | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
Statin ( −) patients (n = 91) | Statin ( +) patients (n = 26) | p value | psmStatin ( −) patients (n = 52) | psmStatin ( +) patients (n = 26) | p value | |||||
Leukocytes [giga/l] | MV | MV | MV | MV | ||||||
POD 0 (on arrival at ICU) | 9.2 (3.6–29.6) | 1 | 8.9 (3.0–24.6) | 0 | 0.5736 | 9.5 (3.7–29.6) | 1 | 8.9 (3.0–24.6) | 0 | 0.5180 |
POD 1 | 10.4 (4.0–23–6) | 1 | 10.7 (5.3–23.1) | 0 | 0.4664 | 10.2 (4.4–23.6) | 0 | 10.7 (5.3–23.1) | 0 | 0.5076 |
POD 2 | 11.2 (1.8–24.6) | 0 | 11.5 (6.7–19.0) | 0 | 0.4607 | 10.4 (1.8–24.6) | 0 | 11.5 (6.7–19.0) | 0 | 0.4297 |
POD 3 | 8.9 (4.4–34.1) | 8 | 9.5 (1.9–17.9) | 0 | 0.9010 | 8.9 (4.4–34.1) | 2 | 9.5 (1.9–17.9) | 0 | 0.8652 |
POD 4 | 7.6 (3.9–106.0) | 14 | 8.4 (2.7–18.2) | 1 | 0.5285 | 7.4 (3.9–106.0) | 7 | 8.4 (2.7–18.2) | 1 | 0.5728 |
POD 5 | 7.7 (3.4–21.5) | 23 | 8.4 (3.9–16.7) | 2 | 0.5572 | 7.7 (3.4–16.6) | 13 | 8.4 (3.9–16.7) | 2 | 0.7989 |
POD 6 | 8.7 (3.4–23.1) | 26 | 9.9 (5.8–15.2) | 5 | 0.2070 | 9.3 (3.4–19.2) | 12 | 9.9 (5.8–15.2) | 5 | 0.5286 |
POD 7 | 9.4 (3.0–29.0) | 25 | 10.7 (5.4–15.8) | 5 | 0.2578 | 9.8 (3.0–29.0) | 16 | 10.7 (5.4–15.8) | 5 | 0.4923 |
POD 8 | 11.0 (4.1–33.3) | 36 | 11.0 (5.9–22.4) | 5 | 0.8800 | 10.7 (4.1–31.5) | 17 | 11.0 (5.9–22.4) | 5 | 0.8990 |
POD 9 | 11.6 (4.5–49.7) | 30 | 11.5 (6.2–22.3) | 3 | 0.8923 | 12.3 (4.9–40.7) | 17 | 11.5 (6.2–22.3) | 3 | 0.8115 |
POD 10 | 13.0 (4.2–38.7) | 37 | 11.3 (7.1–28.2) | 5 | 0.7101 | 12.4 (4.7–37.8) | 18 | 11.3 (7.1–28.2) | 5 | 0.7950 |
C-reactive protein [mg/l] | MV | MV | MV | MV | ||||||
POD 0 (on arrival at ICU) | 5.2 (0–256.0) | 1 | 5.2 (0.5–106.7) | 2 | 0.7730 | 8.7 (0.0–256.0) | 0 | 5.2 (0.5–106.7) | 2 | 0.6670 |
POD 1 | 93.4 (31.2–226.2) | 1 | 88.4 (48.9–155.3) | 0 | 0.8296 | 94.4 (35.4–226.2) | 0 | 88.4 (48.9–155.3) | 0 | 0.7385 |
POD 2 | 202.8 (55.3–359.4) | 0 | 211.0 (110.7–329.3) | 0 | 0.2472 | 194.0 (55.3–359.4) | 0 | 211.0 (110.7–329.3) | 0 | 0.2091 |
POD 3 | 185.1 (68.5–365.4) | 8 | 234.1 (26.3–403.9) | 0 | 0.1290 | 186.3 (68.5–365.4) | 2 | 234.1 (26.3–403.9) | 0 | 0.0683 |
POD 4 | 156.9 (30.1–405.8) | 14 | 194.3 (85.8–410.0) | 1 | 0.0557 | 156.9 (51.4–405.8) | 7 | 194.3 (85.8–410.0) | 1 | 0.0931 |
POD 5 | 138.1 (25.4–348.0) | 23 | 150.1 (40.7–539.1) | 2 | 0.4632 | 139.9 (25.4–345.2) | 13 | 150.1 (40.7–539.1) | 2 | 0.4748 |
POD 6 | 124.5 (6.0–423.2) | 25 | 148.8 (36.8–390.9) | 5 | 0.3188 | 123.8 (14.1–423.2) | 12 | 148.8 (36.8–390.9) | 5 | 0.3351 |
POD 7 | 122.5 (8.3–445.1) | 25 | 135.4 (19.9–316.4) | 5 | 0.4019 | 133.7 (8.3–445.1) | 16 | 135.4 (19.9–316.4) | 5 | 0.6611 |
POD 8 | 147.1 (6.0–431.8) | 36 | 213.6 (12.0–491.9) | 5 | 0.4714 | 147.1 (6.0–431.8) | 17 | 213.6 (12.0–491.9) | 5 | 0.6116 |
POD 9 | 138.2 (5.6–412.9) | 32 | 153.2 (22.1–446.9) | 3 | 0.3319 | 138.2 (5.6–412.9) | 17 | 153.2 (22.1–446.9) | 3 | 0.4550 |
POD 10 | 148.7 (4.9–393.9) | 37 | 159.8 (22.9–310.5) | 5 | 0.3018 | 127.2 (8.1–393.9) | 18 | 159.8 (22.9–310.5) | 5 | 0.2638 |