From: Perioperative statin medication impairs pulmonary outcome after abdomino-thoracic esophagectomy
Variable | All patients | Propensity score-matched patients | ||||
---|---|---|---|---|---|---|
Statin ( −) patients (n = 91) | Statin ( +) patients (n = 26) | p value | psmStatin ( −) patients (n = 52) | psmStatin ( +) patients (n = 26) | p value | |
Main procedure | ||||||
COS | 63a (69.2%) | 23 (88.5%) | 0.0758 | 41 (78.8%) | 23 (88.5%) | 0.3633 |
LAE | 28 (30.8%) | 3 (11.5%) | 11 (21.2%) | 3 (11.5%) | ||
Thoracic anastomosis | 88a (96.7%) | 20 (76.9%) | 0.0037 | 50 (96.2%) | 20 (76.9%) | 0.0145 |
Cervical anastomosis | 3 (3.3%) | 6 (23.1%) | 2 (3.8%) | 6 (23.1%) | ||
Lymph node dissection | 91 (100%) | 26 (100%) | 1 | 52 (100%) | 26 (100%) | 1 |
Relevant abdomino/thoracic extended procedures (additional to esophagectomy) [n] | Major lung resection: 1 | Major lung resection: 1 | Major lung resection: 0 | Major lung resection: 1 | ||
Minor lung resection: 4 | Minor lung resection: 2 | Minor lung resection: 4 | Minor lung resection: 2 | |||
Minor liver resection: 9 | Minor liver resection: 2 | Minor liver resection: 4 | Minor liver resection: 2 | |||
Jejunum catheter: 3 | Jejunum catheter: 1 | Jejunum catheter: 2 | Jejunum catheter: 1 | |||
Cholecystectomy: 4 | Cholecystectomy: 0 | Cholecystectomy: 2 | Cholecystectomy: 0 | |||
Colon resection: 2 | Colon resection: 1 | Colon resection: 0 | Colon resection: 1 | |||
Appendectomy: 2 | Appendectomy: 0 | Appendectomy: 1 | Appendectomy: 0 | |||
Omentectomy: 3 | Omentectomy: 1 | Omentectomy: 1 | Omentectomy: 1 | |||
Left adrenalectomy: 1 | Left adrenalectomy: 0 | Left adrenalectomy: 0 | Left adrenalectomy: 0 | |||
Other minor resections: 4 | Other minor resections: 2 | Other minor resections: 1 | Other minor resections: 2 | |||
n patients | 27 (29.7%) | 9 (34.6%) | 0.6366 | 13 (25.0%) | 9 (34.6%) | 0.4286 |
Duration of the thoracic part of esophagectomy procedure [min] | 126 (67–423) | 127.5 (45.0–228.0)b | 0.2078 | 119.5 (67.0–304.0) | 127.5 (45.0–228.0)b | 0.5955 |
Total duration of surgery [min] | 297 (177–635) | 296 (191–537) | 0.9556 | 285.5 (177.0–534.0) | 296.0 (191.0–537.0) | 0.7829 |
Blood loss [ml] | 500 (50–2500) | 600 (200–4800) | 0.3454 | 505 (100–2500) | 600 (200–4800) | 0.4501 |
IO transfusion [n pat] | 24 (26.4%) | 5 (19.2%) | 0.6084 | 16 (30.8%) | 5 (19.2%) | 0.4172 |
PO transfusion [n pat] | 24 (26.4%) | 12 (46.2%) | 0.0898 | 16 (30.8%) | 12 (46.2%) | 0.2156 |
Peridural anesthesia | 69 (75.8%) | 18 (69.2%) | 0.6109 | 35 (67.3%) | 18 (69.2%) | 1 |