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Table 1 Preoperative description of patients submitted to cardiopulmonary exercise testing (CPET) prior to major abdominal surgery and summary of CPET outcomes. SD, standard deviation; IQR, interquartile range

From: The Marsden Morbidity Index: the derivation and validation of a simple risk index scoring system using cardiopulmonary exercise testing variables to predict morbidity in high-risk patients having major cancer surgery

Variable

Overall patients (n = 1398)

 

Median (range)

Age (years)

 Median (range), (IQR)

68 (21–89), (65–78)

Body mass index (BMI)

 Mean (SD)

27.98 (5.87)

 Median (range), (IQR)

28.0 (12.3–48.4), (24.3–32.0)

Anaerobic threshold (AT)

 Mean (SD)

10.79 (2.01)

 Median (range), (IQR)

10.4 (5.5–19.9), (10.0–12.6)

VO2 max

 Mean (SD)

17.11 (5.74)

 Median (range), (IQR)

15.8 (4.5–37.6), (13.9–18.9)

AT VE/VCO2

 Mean (SD)

35.68 (4.39)

 Median (range), (IQR)

36 (20–48) [32–38],

Oxygen pulse

 Mean (SD)

9.63 (3.00)

 Median (range), (IQR)

9 (2–14) [9–13],

 

n(%)

Age group

 ≤ 50 years

164 (12)

 51–70 years

722 (52)

 > 70 years

512 (37)

Gender

 Female

694 (50)

 Male

704 (50)

BMI standard categories

 < 18.5

203 (14)

 18.5–24.99

199 (14)

 ≥ 25.0

996 (71)

Surgery type

 Robotic/laparoscopic

356 (25)

 Open

1,042 (75)

American Society of Anaesthesiologists (ASA) score

 ASA 1

22 (2)

 ASA 2

1,076 (77)

 ASA 3

300 (21)

World Health Organisation (WHO) category

 0

735 (53)

 1

565 (40)

 2

53 (4)

 3

43 (3)

 4

2 (0.1)

Arrhythmia

 No

1,246 (89)

 Yes

152 (11)

Documented cirrhosis

 No

1,307 (93)

 Yes

91 (7)

Congestive cardiac failure

 No

1,358 (97)

 Yes

40 (3)

Diabetic status

 Negative

1,034 (74)

 Non-insulin

306 (22)

 Insulin dependent

58 (4)

Chronic obstructive pulmonary disease (COPD)

 No

862 (62)

 Yes

536 (38)

Previous cardiac event

 No

975 (70)

 Yes

423 (30)

Prior transient ischaemic attack (TIA) or stroke

 No

1,269 (91)

 Yes

129 (9)

Chronic renal impairment

 No

1,147 (82)

 Yes

251 (18)

Number of procedures

 1

782 (56)

 2

154 (11)

 ≥ 3

462 (33)

Cancer stage (TNM classification)

 Primary cancer

1,234 (88)

 Local nodal metastases

140 (10)

 Distant metastases

23 (2)

Surgical categories

 Hepatobiliary

228 (16)

 Urology

340 (24)

 General surgery

330 (24)

 Colorectal/lower gastrointestinal (GI)

118 (8)

 Upper gastrointestinal (GI)

234 (17)

 Gynaecological

138 (10)

 Sarcoma

9 (0.6)