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Table 3 Univariate analysis for the development of delayed neurocognitive recovery at post-op 3 day

From: The effect of opioid-sparing anesthesia regimen on short-term cognitive function after thoracoscopic surgery: a prospective cohort study

  Patients with DNR at 3rd day (n = 24) Patients without DNR at 3rd day (n = 36) Statistics P value
Male (n (%)) 12 (50%) 20 (55.5%) 0.096 0.798
Age (years) 61 ± 8 48 ± 14 3.881 <0.001*
ASA = 2 (n (%)) 16 (66.7%) 19 (52.8%) 1.396 0.294
Hypertension (n (%)) 13 (54.1%) 5 (13.9%) 11.566 0.001*
Nerve blocks    2.5 0.187
 ESPB group (n = 30) 9 (37.5%) 21 (58.3%)   
 Control group (n = 30) 15 (62.5%) 15 (41.6%)   
Sufentanil dose during surgery (μg/kg) 0.40 ± 0.12 0.35 ± 0.13 1.977 0.05
Remifentanil dose during surgery (μg/kg/min) 0.07 ± 0.04 0.06 ± 0.03 1.324 0.188
Resting pain score at 24h 1 (0, 1) 1 (0, 2) − 0.364 0.716
Coughing pain score at 24h 3 (2.5, 3) 3 (3, 3) − 0.339 0.735
Cumulative equivalent sufentanil dose at 48 h (μg/kg) 0.74 ± 0.18 0.66 ± 0.26 0.989 0.330
Chest tube drainage (days) 2 (2, 3) 3 (2, 3.5) − 0.790 0.429
Hospital stay (days) 3 (3, 4) 4 (3, 5) − 1.238 0.216
Education years less than 9 18 (75%) 6 (16.7%) 18.929 <0.001*
Smoking (n (%)) 11 (45.8%) 7 (19.4%) 5.070 0.043*
Drinking (n (%)) 12 (50%) 7 (19.4%) 6.577 0.022*
Postoperative Cogstate test
 Detection (log10 ms) 2.96 ± 0.07 2.71 ± 0.07 12.329 <0.001*
 Identification (log10 ms) 3.06 ± 0.07 2.87 ± 0.09 7.817 <0.001*
 One-card learning (arcsine accuracy) 0.89 ± 0.09 0.92 ± 0.08 − 2.086 0.204
 One-back memory (arcsine accuracy) 1.10 ± 0.20 1.15 ± 0.25 − 0.781 0.439
  1. DNR delayed neurocognitive recovery. Data are shown as mean ± SD, median (Q1, Q3), or numbers (%). *P < 0.05