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Table 4 Total fluid volumes, vasopressor doses and perioperative blood transfusion

From: Effect of goal-directed haemodynamic therapy guided by non-invasive monitoring on perioperative complications in elderly hip fracture patients within an enhanced recovery pathway

  Control (CG)
n=272
Intervention (IG)
n=279
p-value
n (%) Median (IQR) n (%) Median (IQR)  
Fluid volumes
Total fluids (ml) 272 (100%) 2600 (IQR 1700 to 2700) 279 (100%) 850 (IQR 750 to 1050) 0.001
  Fluid creep -antibiotic prophylaxis- (ml) 272 (100%) 200 (IQR 200 to 200) 279 (100%) 200 (IQR 100 to 200) 0.001
  Intraoperative fluids (ml) 272 (100%) 2500 (IQR 2000 to 2500) 279 (100%) 700 (IQR 550 to 900) 0.001
Crystalloids (ml) 253 (94.5%) 2000 (IQR 2000 to 2000) 278 (99.6%) 650 (IQR 550 to 850) 0.001
  Saline (ml) 68 (25.0%) 1000 (IQR 1000 to 1000) 267 (95.7%) 650 (IQR 550 to 850) 0.001
  Lactated Ringer (ml) 201 (73.9%) 1000 (IQR 1000 to 1000) 12 (4.3%) 1050 (IQR 850 to 1237) 0.889
  Isofundin® (ml) 22 (8.1%) 500 (IQR 500 to 500) - - -
Colloids (ml) 161 (59.2%) 500 (IQR 500 to 500) 25 (9.0%) 300 (IQR 200 to 500) 0.001
  Voluven® (ml) 153 (56.3%) 500 (IQR 500 to 500) 25 (9.0%) 300 (IQR 200 to 500) 0.001
  Gelaspan® (ml) 11 (4.0%) 500 (IQR 500 to500) - - -
Vasopressor 108 (39.7%)   71 (25.5%)   <0.001
  Ephedrine (mg) 108 (39.7%) 15 (IQR 10 to 30) 65 (23.3%) 10 (IQR 10 to 20) 0.002
  Phenylephrine (mg) - - 11 (4.0%) 100 (IQR 50 to 150) -
  Noradrenaline (mg) 2 (0.7%) 3.5 (IQR 2 to 3.5) - - -
Blood transfusion 200 (73.5%) - 124 (44.4%) - <0.001
  Number of PRBCa   2 (IQR 2 to 4)   2 (IQR 1 to 2) <0.001
Fluid Challenge Responder - - 82 (29.4%)   -
  1. Median (IQR 25th percentile to 75th percentile)
  2. PRBC packed red blood cells
  3. aAbout transfused patients