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Table 3 Main and secondary outcomes at 1-year follow-up

From: Effect of goal-directed haemodynamic therapy guided by non-invasive monitoring on perioperative complications in elderly hip fracture patients within an enhanced recovery pathway

 

Control (CG)

n=272

Intervention (IG)

n=279

p-value

Intraoperative complications

 Hemodynamic instability

102 (37.5%)

78 (28.0%)

0.017a

 No. of episodes of hemodynamic instabilitye

2 (IQR 1 to 4)

1 (IQR 1 to 2)

<0.001b

 Arrhythmias

6 (2.2%)

2 (0.7%)

0.172c

Postoperative complications

123 (45.2%)

118 (42.3%)

0.489a

Cardiovascular

51 (18.8%)

20 (7.2%)

<0.001a

  Major

12 (4.4%)

11 (3.9%)

0.783a

   Myocardial infarction

1 (0.4%)

0 (0.0%)

0.494c

   Cardiorespiratory arrest

3 (1.1%)

6 (2.2%)

0.505c

   Acute pulmonary edema

8 (2.9%)

5 (1.8%)

0.374a

   Pulmonary thromboembolism

0 (0.0%)

0 (0.0%)

-

   Cardiorespiratory arrest

0 (0.0%)

0 (0.0%)

-

  Minor

40 (14.7%)

12 (4.3%)

<0.001a

   Haemodynamic instability

34 (12.5%)

5 (1.8%)

<0.001a

   Arrhythmias

4 (1.5%)

7 (2.5%)

0.384a

   Others

2 (0.7%)

1 (0.4%)

0.620c

Respiratory

41 (15.1%)

10 (3.6%)

<0.001a

  Hypoxia

17 (6.3%)

2 (0.7%)

<0.001a

  Decompensation of chronic obstructive pulmonary disease

6 (2.2%)

1 (0.4%)

0.066c

  Acute respiratory infection

16 (5.9%)

5 (1.8%)

0.012a

  Others

3 (1.1%)

2 (0.7%)

0.682c

Renal

33 (12.1%)

94 (33.7%)

<0.001a

Infections

57 (21.0%)

11 (3.9%)

<0.001a

   Surgical wound

8 (2.9%)

0 (0.0%)

0.003c

   Urinary

47 (17.3%)

10 (3.6%)

<0.001a

   Systemic

3 (1.1%)

2 (0.7%)

0.682a

Secondary to spinal anaesthesia

 Hematoma/infection/neurological lesion

0 (0.0%)

0 (0.0%)

-

Surgical reintervention

6 (2.2%)

0 (0.0%)

0.014c

Length of stay (days)

11 (IQR 8 to 16)

8 (IQR 6 to 11)

<0.001b

Destination after discharge

  

0.327a

 Convalescence

128 (49.8%)

142 (52.0%)

 

 Family home

81 (31.5%)

71 (26.0%)

 

 Residence

48 (18.7%)

60 (22.0%)

 

Thirty-day readmission

29 (11.3%)

21 (7.7%)

0.157a

Survival

  

0.003d

 1 month

91.2% (87.1 to 94.0%)

96.8% (93.9 to 98.3%)

 

 3 months

88.6% (84.2 to 91.8%)

95.3% (92.1 to 97.3%)

 

 6 months

83.0% (78.0 to 87.0%)

90.2% (86.0 to 93.2%)

 

 12 months

73.4% (67.7 to 78.3%)

83.8% (78.8 to 87.7%)

 
  1. Mean ± Standard deviation; n (%); median (range x to y) or median (IQR 25th percentile to 75th percentile)
  2. a Pearson χ2; b Mann–Whitney U; c Fisher’s exact test; d Log-rank test
  3. eIn patients with haemodynamic instability