Effect of the preoperative physical status on postoperative nausea and vomiting risk: a matched cohort study

Table 4 Unadjusted, all variables adjusted, and all variables and propensity score-adjusted Association of American Society of Anesthesiologists Physical Status (ASA-PS)

			HR (95% CI) ASA PS 1 vs. 2	P value	HR (95% CI) ASA PS 1 vs. 3	P value	HR (95% CI) ASA PS 2 vs. 3	P value
Original data analysis	PONV	Unadjusted	0.97 (0.93–1.01)	0.09	0.79 (0.74–0.85)	< 0.001	0.87 (0.82–0.92)	< 0.001
		AV adjusted	0.96 (0.93–1.0)	0.07	0.76 (0.71–0.82)	< 0.001	0.86 (0.82–0.91)	< 0.001
		AVP adjusted	0.96 (0.93–1.0)	0.07	0.76 (0.71–0.82)	< 0.001	0.86 (0.82–0.91)	< 0.001
	PV	Unadjusted	1.13 (1.02–1.25)	0.02	1.14 (0.96–1.34)	0.14	1.09 (0.96–1.23)	0.17
		AV adjusted	1.12 (1.02–1.25)	0.02	1.08 (0.92–1.28)	0.35	1.07 (0.95–1.21)	0.26
		AVP adjusted	1.12 (1.01–1.25)	0.02	1.08 (0.92–1.28)	0.34	1.08 (0.95–1.21)	0.24
Sensitivity analysis	PONV	Unadjusted	0.92 (0.88–0.96)	< 0.001	0.69 (0.63–0.75)	< 0.001	0.86 (0.81–0.91)	< 0.001
		AV adjusted	0.92 (0.88–0.96)	< 0.001	0.68 (0.63–0.74)	< 0.001	0.85 (0.81–0.9)	< 0.001
		AVP adjusted	0.92 (0.88–0.96)	< 0.001	0.68 (0.63–0.74)	< 0.001	0.86 (0.81–0.9)	< 0.001
	PV	Unadjusted	1.02 (0.92–1.14)	0.72	0.99 (0.82–1.19)	0.88	1.1 (0.97–1.24)	0.13
		AV adjusted	1.02 (0.91–1.14)	0.74	0.96 (0.80–1.16)	0.7	1.08 (0.96–1.22)	0.19
		AVP adjusted	1.02 (0.92–1.14)	0.7	0.96 (0.80–1.16)	0.69	1.09 (0.96–1.23)	0.17

In a matched cohort of patients, the association of ASA-PS class with PONV and PV was assessed using multivariable Cox proportional hazard regression
PONV postoperative nausea and vomiting, PV postoperative vomiting, HR hazard ratio, CI confidence interval, ASA-PS American Society of Anesthesiologists Physical Status, AV all variables, AVP all variables + propensity score

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