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Table 1 Patient charcteristics

From: Effect of sedative premedication with oral midazolam on postanesthesia care unit delirium in older adults: a secondary analysis following an uncontrolled before-after design

 

Midazolam cohort

(n = 214)

Non-midazolam cohort

(n = 218)

P

Year of enrollment

 2015

190 (88.8)

 

 2016

24 (11.2)

 

 2017

 

39 (17.9)

 2018

 

179 (82.1)

Baseline characteristics

 Age, years

67 ± 4

67 ± 5

0.204

 Body mass index

26.7 ± 3.5

26.2 ± 3.1

0.212

Education

  

0.064

 Graduation from highschool

118 (55.1)

117 (53.7)

 

 No graduation from highschool

91 (42.5)

101 (46.3)

 

 Not available

5 (2.3)

0 (0.0)

 

Mini-mental Status Examination

29 ± 1

29 ± 1

< 0.001

Patient Health Questionnaire 9

4 ± 3

3 ± 3

0.197

ASA physical status

  

< 0.001

 I

43 (20.1)

21 (9.6)

 

 II

133 (62.1)

176 (80.7)

 

 III

38 (17.8)

21 (9.6)

 

Comorbid conditions

 Arterial hypertension

113 (52.8)

122 (56.0)

0.510

 Coronary heart disease

25 (11.7)

20 (9.2)

0.394

 Congestive heart failure

2 (0.9)

3 (1.4)

1.000

 Chronic kidney disease

7 (3.3)

2 (0.9)

0.104

 Diabetes mellitus

11 (5.1)

17 (7.8)

0.262

 Dyslipoproteinemia

59 (27.6)

56 (25.7)

0.700

 Chronic obstructive pulmonary disease

10 (4.7)

5 (2.3)

0.199

 Current smoking status

17 (7.9)

17 (7.8)

0.955

Surgery and anesthesia

 Type of surgery

  

0.562

 Robot-assisted radical prostatectomy

103 (48)

111 (51)

 

 Open retropubic radical prostatectomy

111 (52)

107 (49)

 

 Duration of surgery, min

191 ± 46

177 ± 33

0.002

 Estimated blood loss, ml

670 ± 522

542 ± 404

0.015

 Anesthesia maintenance

  

< 0.001

 Sevoflurane

121 (57)

216 (99)

 

 Propofol

93 (44)

2 (1)

 

 Duration of anesthesia, min

272 ± 53

250 ± 40

< 0.001

 Administered fluids, ml

2738 ± 816

2573 ± 636

0.054

 Sufentanil (μg kg−1 h−1)

0.23 ± 0.05

0.25 ± 0.05

0.003

  1. Baseline characteristics and variables related to anesthesia and surgery in patients, who received midazolam preoperatively (midazolam cohort) and patients without midazolam for sedative premedication (non-midazolam cohort)