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Table 1 Patient charcteristics

From: Effect of sedative premedication with oral midazolam on postanesthesia care unit delirium in older adults: a secondary analysis following an uncontrolled before-after design

  Midazolam cohort
(n = 214)
Non-midazolam cohort
(n = 218)
P
Year of enrollment
 2015 190 (88.8)  
 2016 24 (11.2)  
 2017   39 (17.9)
 2018   179 (82.1)
Baseline characteristics
 Age, years 67 ± 4 67 ± 5 0.204
 Body mass index 26.7 ± 3.5 26.2 ± 3.1 0.212
Education    0.064
 Graduation from highschool 118 (55.1) 117 (53.7)  
 No graduation from highschool 91 (42.5) 101 (46.3)  
 Not available 5 (2.3) 0 (0.0)  
Mini-mental Status Examination 29 ± 1 29 ± 1 < 0.001
Patient Health Questionnaire 9 4 ± 3 3 ± 3 0.197
ASA physical status    < 0.001
 I 43 (20.1) 21 (9.6)  
 II 133 (62.1) 176 (80.7)  
 III 38 (17.8) 21 (9.6)  
Comorbid conditions
 Arterial hypertension 113 (52.8) 122 (56.0) 0.510
 Coronary heart disease 25 (11.7) 20 (9.2) 0.394
 Congestive heart failure 2 (0.9) 3 (1.4) 1.000
 Chronic kidney disease 7 (3.3) 2 (0.9) 0.104
 Diabetes mellitus 11 (5.1) 17 (7.8) 0.262
 Dyslipoproteinemia 59 (27.6) 56 (25.7) 0.700
 Chronic obstructive pulmonary disease 10 (4.7) 5 (2.3) 0.199
 Current smoking status 17 (7.9) 17 (7.8) 0.955
Surgery and anesthesia
 Type of surgery    0.562
 Robot-assisted radical prostatectomy 103 (48) 111 (51)  
 Open retropubic radical prostatectomy 111 (52) 107 (49)  
 Duration of surgery, min 191 ± 46 177 ± 33 0.002
 Estimated blood loss, ml 670 ± 522 542 ± 404 0.015
 Anesthesia maintenance    < 0.001
 Sevoflurane 121 (57) 216 (99)  
 Propofol 93 (44) 2 (1)  
 Duration of anesthesia, min 272 ± 53 250 ± 40 < 0.001
 Administered fluids, ml 2738 ± 816 2573 ± 636 0.054
 Sufentanil (μg kg−1 h−1) 0.23 ± 0.05 0.25 ± 0.05 0.003
  1. Baseline characteristics and variables related to anesthesia and surgery in patients, who received midazolam preoperatively (midazolam cohort) and patients without midazolam for sedative premedication (non-midazolam cohort)