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Table 2 Postoperative nausea and vomiting in hospital and after discharge

From: Effects of ramosetron orally disintegrating tablets on the prophylaxis of post-discharge nausea and/or vomiting in female patients undergoing day surgery under general anesthesia: a randomized controlled trial

 

Control (n = 67)

Ramosetron (n = 67)

P value

Postoperative 0–0.5 h

 Nausea

9 (13%)

4 (6%)

0.144

 Vomiting

2 (3%)

0 (0%)

0.496

 Nausea, VNRS

8 (22)

3 (11)

0.110

 IV ramosetron

5 (8%)

1 (2%)

0.208

Postoperative 0.5–3 h

 Nausea

16 (24%)

17 (25%)

0.841

 Vomiting

1 (2%)

2 (3%)

1.000

 Nausea, VNRS

7 (18)

6 (13)

0.736

 IV ramosetron

3 (5%)

2 (3%)

1.000

 IV metoclopramide

2 (3%)

0 (0%)

0.496

Post-discharge 24 h

 Nausea

22 (33%)

9 (13%)

0.008

 Vomiting

1 (2%)

2 (3%)

1.000

 Nausea, VNRS

14 (23)

5 (16)

0.011

 Oral metoclopramide

12 (18%)

4 (6%)

0.033

 Oral metoclopramide (mg)

2.4 (5.8)

0.6 (2.4)

0.021

Post-discharge 24–48 h

 Nausea

9 (13%)

5 (8%)

0.259

 Vomiting

0 (0%)

1 (2%)

1.000

 Nausea, VNRS

5 (14)

4 (15)

0.673

 Oral metoclopramide

4 (6%)

1 (2%)

0.365

 Oral metoclopramide (mg)

0.9 (4.2)

0.1 (1.2)

0.162

 Patient satisfaction score

86 (16)

95 (9)

<0.001

  1. Data are expressed as mean (SD) or number of the patients (proportion)
  2. VNRS Verbal numerical rating scale