Clinical covariates that improve surgical risk prediction and guide targeted prehabilitation: an exploratory, retrospective cohort study of major colorectal cancer surgery patients evaluated with preoperative cardiopulmonary exercise testing

Table 5 CPET-derived recovery phase parameters, with difference between survivors and non-survivors after major colorectal cancer surgery at 1-year follow-up

Variables	Survivors	Non-survivors	AUROC	P-value
VO₂: slope (IQR)	0.54 (0.46-0.62)	0.61 (0.57-0.70)	0.74	0.008
Heart rate: slope (IQR)	0.81 (0.74-0.87)	0.89 (0.81-0.95)	0.74	0.006
Ve/VCO₂: slope (IQR)	28.5 (23.90-32.90)	32.1 (24.20-39.40)	0.59	0.318
P_ETCO₂: slope (IQR)	0.95 (0.92-1.00)	0.97 (0.92-1.10)	0.60	0.279

Results are presented as median with IQR
A larger ‘Ve/VCO₂ slope’ implies a slower recovery from peak performance to baseline
VO₂, maximum rate of oxygen consumption measured during incremental exercise; Ve/VCO₂, minute ventilation relationship to carbon dioxide elimination; P_ETCO₂, end tidal partial pressure of carbon dioxide

ISSN: 2047-0525