Preoperative parameters | Dichotomised reference level | N | Hazard ratio or (1/hazard ratio)a | 95%CI | P-value |
---|---|---|---|---|---|
A. Univariable Analysis | |||||
 Charlson Co-morbidity Risk Index | |||||
  i. Continuous |  | 82 | 1.03 | 0.81, 1.32 | 0.810 |
  ii. Dichotomised | < 5 | 82 | 1.62 | 0.54, 4.84 | 0.380 |
 Laboratory parameters | |||||
  i. Continuous | |||||
   • Haemoglobin (g/l) |  | 58 | 0.93, a1.08 | 0.89, 0.98 | 0.001 |
   • White cell count (× 109/l) |  | 58 | 1.29 | 1.08, 1.55 | 0.012 |
   • Neutrophils (× 109/l) |  | 58 | 1.36 | 1.10, 1.67 | 0.010 |
   • Albumin (g/l) |  | 34 | 0.89, a1.12 | 0.80, 1.00 | 0.050 |
   • Modified (neutrophil-albumin) Glasgow Prognostic Score |  | 34 | 3.16 | 1.21, 8.27 | 0.024 |
  ii. Dichotomised | Risk cut-point |  |  |  |  |
   • Haemoglobin (g/l) | <110 | 58 | 0.232, a 4.31 | 0.06, 0.87 | 0.032 |
   • White Cell Count (× 109/l) | > 11 | 58 | 4.40 | 0.91, 21.30 | 0.110 |
   • Neutrophils (× 109/l) | > 7.5 | 58 | 6.79 | 1.68, 27.50 | 0.020 |
   • Platelets (× 109/l) | > 350 | 58 | 2.98 | 0.74, 11.90 | 0.150 |
   • Albumin (g/l) | < 35 | 34 | 0.22, a4.55 | 0.04, 1.12 | 0.051 |
  iii. Ratios | |||||
Neutrophil-lymphocyte ratio (NLR) | > 4 | 58 | 1.57 | 0.42, 5.84 | 0.510 |
Platelet-lymphocyte ratio (PLR) | > 160 | 58 | 0.92 | 0.23, 3.67 | 0.900 |
 CPET-derived parameters | |||||
  i. Continuous | |||||
   • Peak VO2 (ml/kg/min) |  | 82 | 0.91, a1.10 | 0.80, 1.04 | 0.150 |
   • Peak VO2 (ml/min/m2) (× 100) |  | 82 | 0.65, a1.54 | 0.45, 0.94 | 0.012 |
   • VO2 @ AT (ml/kg/min) |  | 82 | 0.89, a1.12 | 0.72, 1.10 | 0.250 |
   • Ve/VCO2 @ AT |  | 82 | 1.09 | 1.02, 1.15 | 0.014 |
   • PETCO2 @ AT (mmHg) |  | 82 | 0.89, a1.12 | 0.82, 0.96 | 0.004 |
  ii. Dichotomised | Risk cut-point |  |  |  |  |
   • Peak VO2 (ml/kg/min) | < 16 | 82 | 0.35, a 2.86 | 0.12, 1.00 | 0.049 |
   • Peak VO2 (ml/min/m2) | < 710 | 82 | 0.13, a7.70 | 0.03, 0.56 | 0.001 |
   • VO2 @ AT (ml/kg/min) | < 12 | 82 | 0.69, a1.45 | 0.23, 2.05 | 0.490 |
   • Ve/VCO2 @ AT | > 35 | 82 | 6.12 | 2.13, 17.50 | 0.001 |
   • PETCO2 @ AT (mmHg) | < 35 | 82 | 0.160, a6.25 | 0.05, 0.47 | 0.002 |
B. Bi-variable analysis | |||||
 • Haemoglobin (g/l) |  |  | 0.94, a1.06 | 0.90, 0.99 | 0.017 |
 • Ve/VCO2 @ AT | >35 | 10 | 2.60 | 0.63, 11.00 | 0.180 |
 • Peak VO2 (ml/min/m2) | <710 | 42 | 0.18 | 0.04, 0.85 | 0.013 |
 • Ve/VCO2 @ AT | > 35 | 13 | a5.56, 3.70 | 1.30, 11.00 | 0.020 |
 • Peak VO2 (ml/min/m2) | > 710 | 28 | 0.11, a9.09 | 0.01, 0.87 | 0.007 |
 • Neutrophils (× 109/l) |  |  | 1.40 | 1.10, 1.70 | 0.008 |