Table 3 Days at Home within 90 days after surgery (DAH-90). Association between the DAH-90, a patient centric measure, and continuous or dichotomised preoperative variables, including the Charlson Co-morbidity score, laboratory biomarkers and CPET-derived variables. Analysis was done using linear regression analysis
Preoperative parameters | Dichotomised reference level | N | beta | 95%CI | P-value |
|---|---|---|---|---|---|
A. Univariable analysis | |||||
 Charlson Co-morbidity Index | |||||
  i. Continuous |  | 80 | − 0.86 | − 2.59, 0.86 | 0.330 |
  ii. Dichotomised | < 5 | 80 | − 4.47 | − 12.10, 3.14 | 0.250 |
 Laboratory parameters | |||||
  i. Continuous | |||||
   • Haemoglobin (g/l) |  | 58 | 0.24 | − 0.01, 0.49 | 0.060 |
   • White cell count (× 109/l) |  | 58 | − 1.94 | − 3.67, − 0.21 | 0.028 |
   • Neutrophils (× 109/l) |  | 58 | − 2.59 | − 4.63, − 0.55 | 0.013 |
   • Albumin (g/l) |  | 34 | 1.37 | 0.57, 2.17 | 0.001 |
   • Modified (neutrophil-albumin) Glasgow Prognostic Score |  | 34 | − 12.50 | − 19.40, − 5.48 | < 0.001 |
  ii. Dichotomised | Risk cut-point |  |  |  |  |
   • Haemoglobin (g/l) | < 110 | 58 | 10.6 | 0.09, 21.00 | 0.048 |
   • White Cell Count (× 109/l | > 11 | 58 | − 26.50 | − 43.40, − 9.55 | 0.002 |
   • Neutrophils (× 109/l | > 7.5 | 58 | − 26.90 | − 41.80, − 11.90 | < 0.001 |
   • Platelets (× 109/l | > 350 | 58 | − 6.27 | − 19.60, 7.07 | 0.360 |
   • Albumin (g/l) | < 35 | 34 | 10.3 | 0.02, 20.60 | 0.050 |
  iii. Ratios | |||||
Neutrophil-lymphocyte ratio (NLR) | > 4 | 58 | − 0.32 | − 9.96, 9.33 | 0.950 |
Platelet-lymphocyte ratio (PLR) | > 160 | 58 | − 2.76 | − 12.70, 7.24 | 0.590 |
 CPET-derived parameters | |||||
  i. Continuous | |||||
   • Peak VO2 (ml/kg/min) |  | 80 | 0.62 | − 0.15, 1.39 | 0.110 |
   • Peak VO2 (ml/min/m2) (× 100) |  | 80 | 2.07 | 0.12, 4.01 | 0.038 |
   • VO2 @ AT (ml/kg/min) |  | 80 | 0.45 | − 0.81, 1.71 | 0.490 |
   • Ve/VCO2 @ AT |  | 80 | − 0.56 | − 1.21, 0.08 | 0.088 |
   • PETCO2 @ AT (mmHg) |  | 80 | 0.68 | 0.05, 1.31 | 0.033 |
  ii. Dichotomised | Risk cut-point |  |  |  |  |
   • Peak VO2 (ml/kg/min) | ≤ 16 | 80 | 10.60 | 3.00, 18.20 | 0.006 |
   • Peak VO2 (ml/min/m2) | < 710 | 80 | 9.46 | 2.08, 16.90 | 0.012 |
   • VO2 @ AT (ml/kg/min) | < 12 | 80 | 1.94 | − 5.88, 9.75 | 0.630 |
   • Ve/VCO2 @ AT | > 35 | 80 | − 13.3 | − 23.7, − 3.01 | 0.011 |
   • PETCO2 @ AT (mmHg) | < 35 | 80 | 11.20 | − 0.08, 22.60 | 0.052 |
B. Bi-variable analysis | |||||
 • Peak VO2 (ml/kg/min) | ≤ 16 | 51 | 19.00 | 11.00, 27.00 | < 0.001 |
 • Modified (neutrophils-albumin) Glasgow Prognostic Score | − 10.00 | − 16.00, − 4.50 | < 0.001 | ||