Postoperative decrease of albumin (ΔAlb) as early predictor of complications after gastrointestinal surgery: a systematic review

Table 1 Characteristics and main outcomes of all included articles (n=16) assessing the predictive role of ΔAlb in terms of postoperative complications

Authors	Year	Design	Surgery	N	Primary outcome	Delta Albumin threshold	MV analysis^a
Mantziari et al.	2015	Prosp	Abdominal	70	Metabolic profile	N/A	Yes^b
Hübner et al.	2016	Prosp	Abdominal	70	Stress response and compl	N/A	N/A
Labgaa et al.	2017	Prosp	Abdominal	138	Stress response	10 g/L	Yes
Kumar et al.	2020	Prosp	Abdominal	50	Compl	N/A	N/A
Müller et al.	2018	Retro	Intestinal	182	Compl	24%	Yes
Galata et al.	2020	Retro	Intestinal	103	Major compl	27%	N/A
Fan et al.	1989	Prosp	Esophagus	40	Compl	N/A	N/A
Labgaa et al.	2020	Retro	Esophagus	1046	Major compl	11 g/L	Yes
Liu et al.	2017	Retro	Gastric	223	Compl.	14%	Yes
Ai et al.	2019	Retro	Gastric	193	Compl	19%	Yes
Giovannini et al.	2006	Prosp	Liver	92	Compl	N/A	N/A
Labgaa et al.	2016	Retro	Liver	106	Compl	N/A	Yes
Hendifar et al.	2016	Retro	Pancreas	106	Compl	N/A	N/A^c
Ge et al.	2017	Retro	Colorectal	626	Compl	15%	Yes
Wierdak et al.	2018	Prosp	Colorectal	105	Infectious compl	5 g/l	N/A
Wang et al.	2018	Retro	Colorectal	193	Major compl	17%	Yes

Compl complications, MV multivariable, N/A no answer, Prosp prospective, Retro retrospective, POPF postoperative pancreatic fistula
^aMultivariable analysis showing ΔAlb to be an independent risk factor
^bΔAlb was not independently associated with postoperative complication
^cFound no association between ΔAlb and complications but with ΔAlb and disease-free survival

ISSN: 2047-0525