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Table 3 A literature review on application of honey in other surgeries

From: Does application of honey improve surgical outcome in pilonidal cyst excision with secondary intention healing? A prospective randomized placebo-controlled clinical trial

  Author Country Year Wound description Number in trial Results
1 Vardi et al. (Vardi et al., 1998) Israel 1998 Post-surgical chronic open wound infection that failed to heal with conventional treatment 9 infants Honey is useful in the treatment of post-surgical wounds that are infected and do not respond to conventional systemic and local antibiotic treatment
2 Al-Waili et al. (Al-Waili & Saloom, 1999) United Arab Emirates 1999 Wound infection following caesarean Section or total abdominal hysterectomy 26 patients were treated with honey and 24 patients with local antiseptics (Ethanol and povidone-iodine) Honey could (1) eradicate bacterial infections faster, (2) reduce period of antibiotic use and hospital stay, (3) accelerate wound healing, (4) prevent wound dehiscence and need for re-suturing, and (5) result in minimal scar formation.
3 McIntosh et al. (McIntosh & Thomson, 2006) UK 2006 Toenail surgery with matrix phenolization 100 participants, 52 received an active manuka honey dressing and 48 received paraffin-impregnated tulle gras Paraffin tulle gras dressings are more effective than honey dressings following partial toenail avulsion
4 Pereira et al. (Pereira et al., 2012) Portugal 2012 A 47-year-old male patient with a loco-regional advanced right pyriform sinus tumour, with skin invasion on the anterior part of the neck, who developed with post laryngopharyngectomy wound dehiscence Case report Honey can be used as an alternative and experimental local therapy
5 Nikpour et al. (Nikpour et al., 2014) Iran 2014 Cesarean section 37 cases of drug and 38 cases of placebo Effective in healing the cesarean section incision.
6 Anyanechi et al. (Anyanechi & Saheeb, 2015) Nigeria 2014 Benign lesions of the mandible, treated by segmental mandibular resection, developing with the surgical wound dehiscence 72 patients, 36 in control, and 36 in experimental group (dressed in honey after debridement) Honey speeds up the healing of dehiscence wounds of resected mandible when used as dressing more than the control.
7 Goharshenasan et al. (Goharshenasan et al., 2016) Iran 2016 Bilateral symmetric incisions in randomly selected plastic surgical patients 72 symmetrical incisions in 52 patients were randomly covered post-operatively with conventional dressing and honey dressing for 5 days The healing process of the surgical wound and its final aesthetic result could be improved by using honey dressing.