| Author | Country | Year | Wound description | Number in trial | Results |
---|---|---|---|---|---|---|
1 | Vardi et al. (Vardi et al., 1998) | Israel | 1998 | Post-surgical chronic open wound infection that failed to heal with conventional treatment | 9 infants | Honey is useful in the treatment of post-surgical wounds that are infected and do not respond to conventional systemic and local antibiotic treatment |
2 | Al-Waili et al. (Al-Waili & Saloom, 1999) | United Arab Emirates | 1999 | Wound infection following caesarean Section or total abdominal hysterectomy | 26 patients were treated with honey and 24 patients with local antiseptics (Ethanol and povidone-iodine) | Honey could (1) eradicate bacterial infections faster, (2) reduce period of antibiotic use and hospital stay, (3) accelerate wound healing, (4) prevent wound dehiscence and need for re-suturing, and (5) result in minimal scar formation. |
3 | McIntosh et al. (McIntosh & Thomson, 2006) | UK | 2006 | Toenail surgery with matrix phenolization | 100 participants, 52 received an active manuka honey dressing and 48 received paraffin-impregnated tulle gras | Paraffin tulle gras dressings are more effective than honey dressings following partial toenail avulsion |
4 | Pereira et al. (Pereira et al., 2012) | Portugal | 2012 | A 47-year-old male patient with a loco-regional advanced right pyriform sinus tumour, with skin invasion on the anterior part of the neck, who developed with post laryngopharyngectomy wound dehiscence | Case report | Honey can be used as an alternative and experimental local therapy |
5 | Nikpour et al. (Nikpour et al., 2014) | Iran | 2014 | Cesarean section | 37 cases of drug and 38 cases of placebo | Effective in healing the cesarean section incision. |
6 | Anyanechi et al. (Anyanechi & Saheeb, 2015) | Nigeria | 2014 | Benign lesions of the mandible, treated by segmental mandibular resection, developing with the surgical wound dehiscence | 72 patients, 36 in control, and 36 in experimental group (dressed in honey after debridement) | Honey speeds up the healing of dehiscence wounds of resected mandible when used as dressing more than the control. |
7 | Goharshenasan et al. (Goharshenasan et al., 2016) | Iran | 2016 | Bilateral symmetric incisions in randomly selected plastic surgical patients | 72 symmetrical incisions in 52 patients were randomly covered post-operatively with conventional dressing and honey dressing for 5 days | The healing process of the surgical wound and its final aesthetic result could be improved by using honey dressing. |