Conservative group (perioperative balance ≤2.5 L), median [IQR] or no. (%) n = 179 | Liberal group (perioperative balance > 2.5 L), median [IQR] or no. (%) n = 163 | |
---|---|---|
Intraoperative data | ||
Fluid variables, mL | ||
iv# crystalloids | 1400 [950, 1830] | 2360 [1600, 3280] |
iv colloids | 0 [0, 0] | 0 [0, 500] |
iv glucose containing fluids | 0 [0, 0] | 0 [0, 0] |
iv blood products | 0 [0, 0] | 0 [0, 0] |
iv other fluids | 110 [60, 170] | 190 [90, 280] |
Total iv fluid administration | 1610 [1120, 2040] | 2750 [2090, 3750] |
Total iv fluid administration (mL kg−1 h−1) | 9.8 [7.5, 12.7] | 13.3 [9.0, 18.2] |
Missing, no. | 3 | 0 |
Diuresis | 120 [0, 380] | 180 [70, 450] |
Blood loss | 0 [0, 130] | 100 [0, 400] |
Other loss | 110 [70, 420] | 120 [80, 260] |
Total loss | 490 [140, 1130] | 600 [310, 1130] |
Fluid balance | 930 [570, 1290] | 2030 [1550, 2790] |
Hypotensive episodes | 79 (44.1) | 105 (64.4) |
Vasopressor given | 156 (87.2) | 152 (93.3) |
Ephedrine, mg, n = 118 / 100§ | 20.0 [10.0, 30.0] | 17.5 [10.0, 30.0] |
Norepinephrine, mg, n = 10 / 40§ | 1.5 [0.4, 3.4] | 2.8 [1.8, 5.0] |
Phenylephrine, mg, n = 94 / 112§ | 1.0 [0.4, 2.2] | 2.8 [1.0, 5.7] |
Postoperative data | ||
Fluid variables, mL | ||
iv crystalloids | 720 [400, 1280] | 1900 [1090, 3170] |
iv colloids | 0 [0, 0] | 0 [0, 400] |
iv glucose | 0 [0, 0] | 0 [0, 230] |
iv blood products | 0 [0, 0] | 0 [0, 0] |
iv other fluids | 180 [5, 350] | 410 [180, 1190] |
Total iv fluid administration | 950 [590, 1510] | 2970 [1710, 5620] |
Total iv fluid administration (mL kg−1 h−1) | 3.5 [2.3, 4.8] | 4.6 [3.7, 6.8] |
Missing, no. | 3 | 1 |
Diuresis | 140 [0, 500] | 530 [110, 1320] |
Blood loss | 0 [0, 0] | 0 [0, 0] |
Other loss | 140 [80, 280] | 340 [140, 770] |
Total loss | 270 [110, 830] | 970 [270, 2240] |
Fluid balance | 520 [250, 850] | 1750 [1110, 3110] |
Hypotensive episodes | 17 (9.5) | 46 (28.4) |
Missing, no. | 0 | 1 |
Vasopressor given | 22 (12.3) | 71 (43.8) |
Ephedrine, mg, n = 6 / 13§ | 15.0 [10.0, 20.0] | 10.0 [10.0, 20.0] |
Norepinephrine, mg, n = 12 / 47§ | 5.9 [3.4, 14.2] | 12.8 [6.2, 20.0] |
Phenylephrine, mg, n = 9 / 19§ | 2.2 [1.0, 8.1] | 3.1 [0.5, 5.9] |
Perioperative fluid data | ||
Epidural analgesia, no. (%) | 77 (43.0) | 70 (42.9) |
Total iv fluid administration | 2610 [2160, 3310] | 6000 [4290, 8930] |
Total iv fluid administration (mL kg−1 h−1) | 5.9 [4.1, 7.8] | 7.3 [5.4, 10.2] |
Missing, no. | 3 | 0 |
Total loss | 920 [480, 2000] | 1900 [960, 3350] |
Fluid balance, mL | 1580 [1000, 2040] | 3620 [3020, 5340] |
Fluid balance, mL kg−1 h−1 | 3.3 [1.7, 5.2] | 4.7 [3.4, 7.2] |
Missing, no. | 3 | 0 |