Impact on grafted kidney function of rocuronium-sugammadex vs cisatracurium-neostigmine strategy for neuromuscular block management. An Italian single-center, 2014-2017 retrospective cohort case-control study

Table 1 Patients’ characteristics

Characteristic	NEO (n = 175)	SUG (n = 175)	P value
Sex, M/F, n (%)	117 (66.9)/58(33.1)	104 (59.4)/71 (40.6)	0.184
Age, years [IQR]	52 [40.5-63]	52 [43.5-60]	0.654
Height, cm [IQR]	170 [165-176]	170 [164-176]	0.355
Weight, kg [IQR]	70 [62-80]	68 [55-78]	0.186
BMI, kg/m² [IQR]	24.22 [22-26.2]	23.6 [20.4-26.1]	0.194
ASA, II/III/IV, n (%)	34 (19.4)/137(78.3)/4 (2.3)	26 (14.9)/148(84.6)/1 (0.6)	0.197
Neurovascular disease, n (%)	6 (3.4)	10 (5.7)	0.444
Respiratory disease, n (%)	18 (10.3)	26 (14.9)	0.195
• Obstructive, n (%)	8 (4.6)	11 (6.3)	0.638
• Other, n (%)	10 (5.7)	15 (8.6)	0.407
Cardiovascular disease, n (%)	137 (78.3)	147 (84)	0.219
• Hypertension, n (%)	124 (70.9)	130 (74.3)	0.549
• Other, n (%)	13 (7.9)	17 (9.7)	0.529
Abdominal disease, n (%)	63 (36)	79 (45.1)	0.102
Impaired glucose tolerance, n (%)	25 (14.3)	30 (17.1)	0.557
Dyslipidaemia, n (%)	30 (17.1)	32 (18.3)	0.889
Other disease, n (%)	16 (9.1)	13 (7.4)	0.699
Previous KTx, n (%)	18 (10.3)	16 (9.1)	0.857

NMB neuromuscular block, NEO group of patients receiving neostigmine for reversal of cisatracurium-induced NMB, SUG group of patients receiving sugammadex for reversal of rocuronium-induced NMB, M male, F female, BMI body mass index, ASA American Society of Anesthesiologists physical status; neurovascular disease: history of transient ischemic attack, stroke, cerebral hemorrhage; respiratory disease: history of asthma, chronic obstructive pulmonary disease, or other diseases (restrictive lung diseases); cardiovascular disease: history of coronary artery disease, arrhythmia, heart failure, hypertension, disorders of the peripheral vascular system; abdominal disease: gastrointestinal disease (history of peptic ulcer, gastroesophageal reflux disease, irritable bowel syndrome, diverticular diseases, colitis, anal disease) and liver disease; other disease: rheumatic disease and musculoskeletal disease. Previous KTx previous kidney transplantation. Data are expressed as median [interquartile range, IQR] or number, n (%)

ISSN: 2047-0525