Table 4 Univariable predictors of all-cause mortality

Age (years)

1.027 (1.01-1.05)

0.002

Female

0.63 (0.43-0.94)

0.02

APACHE-II

1.06 (1.03-1.09)

<0.001

SAPS-II

1.03 (1.02-1.05)

<0.001

Hypertension

1.53 (1.01-2.34)

0.045

Coronary artery disease

1.50 (1.03-2.14)

0.03

Peripheral artery disease

1.97 (1.22-3.17)

0.005

Lactate at ICU admission (mmol/l)

1.080 (1.04-1.12)

<0.001

Lactate at start of CRRT (mmol/l)

1.19 (1.14-1.24)

<0.001

INR at ICU admission

1.45 (1.04-2.02)

0.03

Hemoglobin at start of CRRT

1.01 (1.00-1.02)

0.045

Creatinine at start of CRRT

0.996 (0.994-0.998)

<0.001

CRP at start of CRRT

0.997 (0.996-0.999)

0.007

pH at start of CRRT (per 0.1)

0.94 (0.92-0.96)

<0.001

BE at start of CRRT

0.89 (0.85-0.93)

<0.001

Bicarbonate at start of CRRT

0.86 (0.81-0.91)

<0.001

PaO2/FiO2-ratio at start of CRRT

0.98 (0.97-1.00)

0.02

Highest noradrenaline requirement (ug/kg/min)

1.19 (1.09-1.29)

<0.001

Noradrenaline requirement at ICU admission (ug/kg/min)

1.15 (1.03-1.29)

<0.001

Noradrenaline requirement at start of CRRT (ug/kg/min)

1.32 (1.20-1.47)

<0.001

Number of vasopressors

1.25 (1.02-1.54)

0.04