Variable | Survivors (n = 90) | Non-survivors (n = 67) | p value |
---|---|---|---|
Age (years) | 66.7 ± 12.4 | 71.2 ± 9.7 | 0.01 |
Women n/% | 19/21 | 25/37 | 0.025 |
Hypertension n/% | 59/66 | 50/75 | 0.22 |
Diabetes n/% | 24/27 | 12/18 | 0.20 |
Pulmonary disease n/% | 11/12 | 9/13 | 0.82 |
Coronary artery disease n/% | 29/32 | 32/48 | 0.048 |
Peripheral artery disease n/% | 9/10 | 14/21 | 0.06 |
Malignancy n/% | 10/11 | 2/3 | 0.06 |
Peak SOFA | 14.4 ± 3.1 | 15.7 ± 2.6 | 0.008 |
SAPS-II | 49.2 ± 13.7 | 55.7 ± 11.7 | 0.002 |
APACHE-II | 22.1 ± 6.7 | 26.2 ± 5.3 | < 0.0001 |
Elective operation (n/%) | 22/24.4 | 22/32.8 | 0.25 |
Operation room visits | 2 (1–3) | 2 (1–2) | 0.25 |
Sepsis (n/%) | 31/34.4 | 26/38.8 | 0.57 |
Ventilator days | 8.9 (4.9–13.9) | 4.9 (1.5–9.8) | 0.001 |
Hemoglobin (g/l) | 98 (90–114) | 100 (88–111) | 0.60 |
Leukocytes (E9/l) | 11.4 (8.3–16.45) | 10.6 (8.1–17.3) | 0.86 |
Thrombocytes (E9/l) | 115 (89–170) | 111 (83–163) | 0.50 |
C-reactive protein (mg/l) | 92 (55–190) | 53 (24–214) | 0.14 |
Creatinine (μmol/l) | 191 (122–279) | 151 (119–202) | 0.08 |
Urea (mmol/l) | 10.6 (7.5–18.6) | 9.8 (6.7–17.1) | 0.60 |
Alanine aminotransferase (IU/l) | 33 (18–83) | 25 (14–63) | 0.41 |
Bilirubin (μmol/l) | 15 (9–30) | 18 (11–39) | 0.41 |
International normalized ratio | 1.4 (1.2–1.7) | 1.5 (1.3–1.8) | 0.16 |
pH (U) | 7.32 (7.26–7.36) | 7.31 (7.22–7.35) | 0.06 |
BE (mmol/l) | − 5.4 (− 8.8 to − 3.2) | − 7.2 (− 11.0 to − 3.3) | 0.06 |
Bicarbonate (mmol/l) | 19.7 ± 4.0 | 18.4 ± 4.0 | 0.04 |
Lactate (mmol/l) | 2.5 (1.6–4.2) | 4.2 (2.3–7.4) | 0.0002 |
Sodium (mmol/l) | 136 ± 4 | 137 ± 3 | 0.11 |
Potassium (mmol/l) | 4.4 (3.9–4.9) | 4.3 (3.9–4.8) | 0.39 |
Chloride (mmol/l) | 109 ± 4.7 | 109 ± 4.3 | 0.83 |
Ionized calcium (mmol/l) | 1.10 (1.04–1.14) | 1.09 (1.02–1.16) | 0.89 |
Mean arterial pressure (mmHg) | 73 ± 15 | 70 ± 12 | 0.09 |
Norepinephrine dose (μg/kg/min) | 0.10 (0.03–0.16) | 0.12 (0.03–0.28) | 0.09 |
Maximum norepinephrine dose (μg/kg/min) | 0.20 (0.13–0.33) | 0.33 (0.20–0.53) | < 0.0001 |
Number of vasopressors (n) | 1 (1–2) | 2 (1–3) | 0.03 |