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Table 1 Trial overview and baseline characteristics

From: Deep neuromuscular block reduces the incidence of intra-operative complications during laparoscopic donor nephrectomy: a pooled analysis of randomized controlled trials

 

Participating centers

Recruitment period

Number of patients

IAP (mmHg)

Type of NMBb

Type of anesthesia

Gender

N (%)

ASA classification

N (%)

Age

Mean (SD)

BMI

Mean (SD)

Male

Female

1

2

3

Warle et al. (2013)

RUMC

2011–2012

20

7 vs 14

TOF 1–2

TIVA

10 (50.0%)

10 (50.0%)

17 (85%)

3 (15%)

0 (0%)

51.15 (±9.33)

25.32 (±3.21)

Ozdemir-Van Brunschot et al. (2017)

RUMC

2014–2015

64

6 vs 12

PTC 1–5

Volatile

36 (56.3%)

28 (43.8%)

44 (69%)

20 (31%)

0 (0%)

54.94 (±12.04)

25.92 (±3.19)

Ozdemir-Van Brunschot et al. (2018)

RUMC

2015–2016

34

6

TOF 1–2 vs PTC 1–5

Volatile

22 (64.7%)

23 (35.3%)

N/A

N/A

N/A

50.19 (±12.49)

25.54 (±3.74)

Bruintjes et al. (2019)

RUMC

LUMC

2016–2017

96

12

“Single-dose” vs PTC 1–2

TIVA

45 (46.9%)

51 (53.1%)

61 (64%)

35 (36%)

0 (0%)

56.14 (±9.90)

26.46 (±2.99)

Klop et al. (2014)

EMCR

2011–2012

20a

14

“Single-dose”

TIVA

5 (25.0%)

15 (75.0%)

14 (70%)

5 (25%)

1 (5%)

49.72 (±14.39)

25.09 (±3.19)

Dols et al. (2014)

EMCR

2008–2010

95a

14

“Single-dose”

TIVA

39 (41.1%)

56 (58.9%)

59 (62%)

35 (37%)

1 (1%)

51.59 (±12.99)

25.96 (±4.13)

Dols et al. (2010)

EMCR

RUMC

2006–2008

40

12

“Single-dose”

TIVA

24 (60.0%)

16 (40.0%)

29 (73%)

11 (28%)

0 (0%)

53.41 (±9.62)

26.94 (±3.78)

Minnee et al. (2008)

AUMC

2002–2006

105

12

“Single-dose”

TIVA

44 (41.9%)

61 (58.1%)

85 (81%)

20 (19%)

0 (0%)

47.73 (±11.86)

25.61 (±3.57)

Kok et al. (2006a, b)

EMCR

2001–2004

49a

12

“Single-dose”

TIVA

25 (51.0%)

24 (49.0%)

39 (80%)

10 (20%)

0 (0%)

49.40 (±14.73)

25.73 (±3.57)

Kok et al. (2006a, b)

EMCR

RUMC

2001–2004

50a

12

“Single-dose”

TIVA

18 (52.9%)

16 (47.1%)

N/A

N/A

N/A

47.31 (±13.23)

26.13 (±4.45)

  1. RUMC Radboud University Medical Centre, LUMC Leiden University Medical Centre, EMCR Erasmus Medical Centre Rotterdam, AUMC Amsterdam University Medical Centre, TIVA total intravenous anesthesia, IAP intra-abdominal pressure, NMB neuromuscular blockade, ASA American Society of Anesthesiologists classification system, BMI body mass index
  2. aNumber of patients who underwent laparoscopic donor nephrectomy (transperitoneal approach)
  3. bAll studies used rocuronium as neuromuscular blocking agent