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Table 2 The characteristics of patients

From: The efficacy and safety of antimuscarinics for the prevention or treatment of catheter-related bladder discomfort: a systematic review and meta-analysis of randomized controlled trials

Study

Age (years)

Mean ± SD (Range)

Sex (Male/Female)

Weight (kg)

Mean ± SD

Duration of surgery (min) Mean ± SD

Duration of anesthesia (min) Mean ± SD

Loss to follow-up

Calculation of sample size

Statistical analysis

ITT analysis

EXP

CON

EXP

CON

EXP

CON

EXP

CON

EXP

CON

Agarwal et al. 2005

40.2 ± 13.6

42.6 ± 14.4

33/17

114/51

56.90 ± 8.09

58.24 ± 11.4

NA

NA

0

Yes

T tests; Chi-square test;

No

Agarwal et al. 2006

45.6 ± 13.2; 44.4 ± 12.8

43.6 ± 14.4

40/38;

39/39

42/36

55.4 ± 12.6; 56.9 ± 10.2

57.3 ± 11.4

NA

NA

0

Yes

Chi-square test; ANOVA

No

Tauzin-Fin et al. 2007

65.8 (54-72)

61.1 (54-75)

Male

74.1 ± 9.1

78.1 ± 13.8

188.2 ± 31.3

181.8 ± 33.8

NA

0

Yes

T tests; Chi-square test

No

Ryu et al. 2013

61 (22-70)

61 (24-69)

Male

67 ± 10

70 ± 11

178 ± 66

190 ± 76

224 ± 70

238 ± 82

0

Yes

T tests; Chi-square test

No

Nam et al. 2015

58 ± 10

60 ± 9

Male

69 ± 11

67 ± 9

154 ± 89

160 ± 95

198 ± 95

203 ± 101

0

Yes

Chi-square test; ANOVA

No

Chung et al. 2017

66 (43-84)

68 (26-85)

51/11

61/11

NA

NA

NA

0

Yes

ANOVA; T tests

No

Srivastava et al. 2016

46.8 ± 9.6; 43.0 ± 7.9

48.2 ± 10.2

24/6;

26/4

25/5

63.1 ± 8.6; 65.0 ± 10.3

61.1 ± 9.5

149.8 ± 28.5; 161.5 ± 40.5

156.7 ± 35.8

NA

0

Yes

ANOVA

No

Sabetian et al. 2017

64.95 ± 7.88

63.34 ± 9.22

Male

66.29 ± 6.77

65.61 ± 7.21

73.12 ± 20.42

76.34 ± 23.64

NA

0

Yes

T tests; Chi-square test; ANOVA

No

Maghsoudi et al. 2018

44.4 ± 9.7

44.1 ± 12.2

NA

25.9 ± 3.1 (BMI, kg/m2)

25.0 ± 4.2 (BMI, kg/m2)

97.9 ± 19.7

105.9 ± 23.4

NA

0

Yes

T tests; ANOVA

No

Kim et al. 2016

48.6 ± 12.2

50.2 ± 14.5

29/11

33/10

70.4 ± 12.8

70.2 ± 11.0

18.7 ± 12.2

23.0 ± 15.9

37.9 ± 13.1

39.3 ± 19.1

0

Yes

Chi-square test; Fisher’s exact test; T tests

No

Åžahiner et al. 2020

59.7 ± 2.8

58.7 ± 2.5

25/5

25/5

27.9 ± 3.9 (BMI, kg/m2)

27.2 ± 3.4 (BMI, kg/m2)

41.5 ± 18.8

30.7 ± 14.6

53.3 ± 21.5

38.0 ± 17.8

0

Yes

Mann-Whitney U-test; T-tests; Chi-square test;

No

  1. EXP experimental group, CON control group, ITT intention-to-treat, ANOVA analysis of variance, SD standard deviation, NA not available