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Table 1 The details of individual study

From: The efficacy and safety of antimuscarinics for the prevention or treatment of catheter-related bladder discomfort: a systematic review and meta-analysis of randomized controlled trials

Study

Study design

Therapy in experimental group

Therapy in control group

Sample size

Catheter type

Timing of administration

Anesthesia type

ASA score

Surgery type

Experimental

Control

Agarwal et al. 2005

RCT

Tolterodine 2 mg oral

Placebo

50

165

16 Foley

1 h before induction of anesthesia

General anesthesia

I/II

Urologic surgery for kidney and ureter

Agarwal et al. 2006

RCT

Oxybutynin 5mg / Tolterodine 2 mg oral

Placebo

78/78

78

16 Foley

1 h before induction of anesthesia

General anesthesia

I/II

Percutaneous nephrolithotomy surgery

Tauzin-Fin et al. 2007

RCT

Oxybutynin 5 mg sublingual

Placebo

23

23

16 Foley

Every 8 h for the first 24 h after surgery

General anesthesia

I/II

Radical retropubic prostatectomy

Ryu et al. 2013

RCT

Butyl scopolamine 20 mg iv

Saline

28

29

16/18 Foley

After reporting CRBD

General anesthesia

I/II

Urethrolithotomy, nephrolithotomy and radical retropubic prostatectomy

Nam et al. 2015

RCT

Butyl scopolamine 20 mg iv

None

49

50

14 Foley

Intravenously immediately before the end of the operation

General anesthesia

I/II

Stomach, hepatobiliary, colorectal operation

Chung et al. 2017

RCT

Solifenacin 5 mg oral

None

62

72

18 Foley

The day before, the day of, and the day after surgery

General anesthesia

NA

Transurethral resection of bladder tumor

Srivastava et al. 2016

RCT

Solifenacin 5 mg/Darifenacin 7.5 mg oral

Placebo

30/30

30

16 Foley

1 h prior to induction of anesthesia

General anesthesia

I/II

Elective spine surgery

Sabetian et al. 2017

RCT

Hyoscine N-butyl bromide 20 mg iv

Saline 1ml iv

24

26

22 Foley

Intravenously before the induction of anesthesia

General anesthesia

I/II

Transurethral resection of prostate

Maghsoudi et al. 2018

RCT

Tolterodine 2 mg oral

Vitamin C 250 mg oral

50

70

16 Foley

1 h before surgery

General anesthesia

I

Percutaneous nephrolithotomy

Kim et al. 2016

RCT

Glycopyrrolate 0.3 mg iv

Saline 1.5 ml iv

30

30

16 Foley

Intravenously before the induction of anesthesia

General anesthesia

I/II

Ureteroscopic removal of ureter stone

Åžahiner et al. 2020

RCT

Atropine 15 μg/kg iv

Placebo

30

30

16-20 Foley

The end of the surgery

General anesthesia

I/II/III

Transurethral resection

  1. RCT randomized controlled trial, ASA American Society of Anesthesiologists, NA not available, CRBD catheter related bladder discomfort