Fig. 1From: Electroencephalography-demonstrated mechanisms of dexmedetomidine-mediated deepening of propofol anesthesia: an observational studyExperimental protocol and anesthesia monitoring data. A Experimental flow chart in the operating room. EEG data were collected for two 3-min periods, one commencing 5 min before and one 10 min after dexmedetomidine (Dex) injection during propofol anesthesia. B Comparison of the mean patient state index (PSI) values across the two time points. C Comparison of the mean spectral edge frequency 95 (SEF95) values 5 min before versus 10 min after dexmedetomidine injection. Note that both PSI and SEF95 values were markedly decreased at the second time point relative to the first, consistent with a deepening of anesthesia; ****p < 0.0001, paired t tests. Error bars show the standard deviations (SDs)Back to article page