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Table 5 Association among serum homocysteine, folate, vitamin B12 status and MTHFR SNPs (n = 175)

From: Association between preoperative serum homocysteine and delayed neurocognitive recovery after non-cardiac surgery in elderly patients: a prospective observational study

 

Homocysteine

Folate

Vitamin B12

Parameters

 Homocysteine

–

− 0.360‡

− 0.258†

 Folate

− 0.360‡

–

+ 0.363‡

 Vitamin B12

− 0.258†

+ 0.363‡

–

MTHFR SNPs

 rs1801133

0.253†

− 0.268‡

− 0.020

 rs1801131

− 0.193*

0.107

− 0.060

  1. Spearman’s rank correlation coefficients are presented to describe the association between variables
  2. Abbreviations: MTHFR methylenetetrahydrofolate reductase
  3. *P < 0.05
  4. †P < 0.01
  5. ‡P < 0.001