Table 3 Medication use for total group and comparison of those with and without post-operative hyponatraemia

Warfarin

13 (6.0%)

26 (3.3%)

0.072

39 (3.9%)

Other oral anticoagulants

0 (0%)

7 (0.9%)

0.357

7 (0.7%)

Antiplatelets

79 (36.4%)

221 (28.2%)

0.018

300 (30%)

Steroids

7 (3.2%)

29 (3.7%)

0.747

36 (3.6%)

Hypoglycaemic agents

29 (13.4%)

54 (6.9%)

0.002

83 (8.3%)

Insulin

7 (3.2%)

9 (1.1%)

0.058

16 (1.6%)

PPI/H₂ receptor antagonist

105 (48.4%)

344 (43.9%)

0.221

449 (44.9%)

Bisphosphonate

17 (7.8%)

68 (8.8%)

0.704

85 (8.5%)

Oral calcium

26 (12.0%)

69 (8.8%)

0.153

95 (9.5%)

Levothyroxine

36 (16.6%)

81 (10.3%)

0.011

117 (11.7%)

Oral opioid analgesics

66 (30.4%)

285 (36.3%)

0.111

351 (35.1%)

Opioid analgesic patch

18 (8.3%)

93 (11.9%)

0.142

111 (11.1%)

NSAIDs

68 (31.3%)

248 (31.7%)

0.957

316 (31.6%)

ACEi/ARB

107 (49.3%)

258 (33.3%)

< 0.001

365 (36.5%)

Bendrofluazide/indapamide/CCB/alpha blocker

99 (45.6%)

251 (32.1%)

< 0.001

350 (35.0%)

B-blocker

58 (26.7%)

155 (19.8%)

0.025

213 (21.3%)

Antianginals, digoxin and loop and potassium sparing diuretics

41 (18.9%)

105 (13.4%)

0.040

146 (14.6%)

Statins

97 (44.7%)

294 (37.5%)

0.130

391 (39.1%)

Prostate drugs/drugs for incontinence

16 (7.4%)

88 (11.2%)

0.103

103 (10.3%)

Hypnotics/antidepressants/neuropathic pain/antiepileptics

60 (27.6%)

259 (33.1%)

0.139

319 (31.9%)

Dementia/PD drugs

7 (3.2%)

16 (2.0%)

0.307

23 (2.3%)

Inhalers

28 (12.9%)

103 (13.2%)

0.923

131 (13.1%)

 Flucloxacillin

134 (61.8%)

565 (72.2%)

0.003

699 (69.9%)

 Gentamicin

137 (63.1%)

568 (72.5%)

0.007

705 (70.5%)

 Teicoplanin

80 (36.9%)

215 (27.5%)

0.007

295 (29.5%)